Frontiers in Pharmacology | Drugs Outcomes Research and Policies

Original Research

Published on 11 Apr 2025

From clinical trials to informing clinical decision-making: a review of patient-reported outcomes in nononcology medicines approved by the European Medicines Agency (2018–2022)

in Drugs Outcomes Research and Policies

Sarah Sauchelli
Courtney Levy
Ari Gnanasakthy
Vaidehi Dave
Lynda Doward
Kristina A. Fitzgerald
Robyn Carson

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1536401

Clinical Trial

Published on 11 Apr 2025

Efficacy and safety of intermittent intravenous doxercalciferol in the treatment of secondary hyperparathyroidism in Chinese patients on maintenance hemodialysis: a phase II, open-label, prospective, multicenter study

in Drugs Outcomes Research and Policies

Guang Yang
Yaoyu Huang
Yifei Ge
Xiangbao Yu
Li Liu
Li Xiang
Bin Liu
Chaoqing Gao
Changhua Liu
Yong Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1574679

Original Research

Accepted on 10 Apr 2025

Characteristics, Clinical Evidence and Implementation Effects of Conditional Approvals for Drugs in China, a Pooled Analysis from 2020 to 2023

in Drugs Outcomes Research and Policies

Li Yang
ShuoXin Fan
Jie Zhang
Geyun Huang
Yaoyang Tang
Lijia Xue

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1501525

Original Research

Published on 10 Apr 2025

Impact of clinical pharmacist interventions on medication administration via enteral feeding tubes in a neurology ward: a pre- and post-educational prospective study

in Drugs Outcomes Research and Policies

Yunus Emre Ayhan
Ömer Faruk Özkanlı
Şeyma Gözelizmir
Anmar Al-Taie
Mesut Sancar
Ipek Midi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519835

185 views

Original Research

Accepted on 09 Apr 2025

Towards a Sustainable Rare Disease and Orphan Drug Ecosystem in Saudi Arabia: Policy Insights from a Multi-Stakeholder Workshop

in Drugs Outcomes Research and Policies

Ghada Mohammed Abozaid
Hussain Al-Omar
Abdulaziz Alrabiah
Asma Almuaither
Amy Jayne McKnight

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583477

Perspective

Published on 09 Apr 2025

Exploring the complexities of disproportionality analysis in pharmacovigilance: reflections on the READUS-PV guideline and a call to action

in Drugs Outcomes Research and Policies

Tarek A. Hammad
Melissa Naylor
Dona M. Ely
Simon Davies

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573353

177 views

Original Research

Accepted on 08 Apr 2025

Cost-effectiveness analysis of tislelizumab plus chemotherapy as first-line treatment for HER2-negative advanced gastric or gastro-oesophageal junction adenocarcinoma

in Drugs Outcomes Research and Policies

Liangliang Zou
Cuihua Yuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500729

Original Research

Accepted on 08 Apr 2025

Effective inhaler technique education is achievable -assessment and comparison of five inhaler devices errors

in Drugs Outcomes Research and Policies

Monika Marko
Magdalena Klimczak
Marharyta Sobczak
Maciej Wojakiewicz
Tomasz Dębowski
Andrzej Emeryk
Rafał Pawliczak

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538283

Original Research

Accepted on 08 Apr 2025

Prevalence, risk characteristics, and prediction of low-dose edoxaban treatment in hospitalized patients: a multicenter, observational cohort study

in Drugs Outcomes Research and Policies

Shujuan Zhao
Hengfen Dai
Jiaxin Chen
Ming Ni
Wenxing Peng
Xiaoyu Li
Fen Li
Boya Chen
Haixia Cai
Yinping Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1427634

Original Research

Published on 08 Apr 2025

Potential inappropriate medications and drug–drug interactions in adverse drug reactions in the elderly: a retrospective study in a pharmacovigilance database

in Drugs Outcomes Research and Policies

Huaqiao Jiang
Yanhua Lin
Weifang Ren
Lina Lu
Xiaofang Tan
Xiaoqun Lv
Ning Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546012

235 views

Original Research

Published on 08 Apr 2025

Assessment of competencies of clinical research professionals and proposals to improve clinical research in Portugal

in Drugs Outcomes Research and Policies

Mónica Bogas
Joana Antas
Cátia Magalhães
Mafalda Revige
Liliana Guerra
Cheila Ribeiro
Rita Cunha Eça
Filipa Nunes
Ana Lopes
Luís Costa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578955

205 views

Systematic Review

Accepted on 07 Apr 2025

Cost-effectiveness analysis of Amivantamab plus Lazertinib, Lazertinib versus Osimertinib in NSCLC with EGFR

in Drugs Outcomes Research and Policies

Yueyun Li
Liu Yuhang
Hui Zhang
Haonan Li
Hong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1527614

Original Research

Published on 07 Apr 2025

Drug-therapy-related problems and pharmacist interventions in the medical ward in northeast Ethiopia: focus on types, acceptability, and impacts

in Drugs Outcomes Research and Policies

Bedilu Linger Endalifer
Yared Dergu Ayta
Abate Wondesen Tsigie
Yehualashet Teshome Wondmkun
Mekuanint Terefe Kassa
Gedefaw Getnet Amare
Yenesew Wudu Ejigu
Manaye Tamrie Derseh
Abyou Seyfu Ambaye

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558864

218 views

Original Research

Published on 07 Apr 2025

Economic costs and medications for diabetes in older patients in Beijing, China: electronic insurance data analysis

in Drugs Outcomes Research and Policies

Yanhua Ma
Yan Zhao
Ran Wei
Jingtao Qiao
Jingyi Luo
Lina Zhang
Jie Zhang
Mingqun Deng
Yang Yu
Weihao Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549244

187 views

Original Research

Published on 03 Apr 2025

Argatroban in patients with acute ischemic stroke with early neurological deterioration: a cost-effectiveness analysis from the perspective of Chinese healthcare system

in Drugs Outcomes Research and Policies

Yu Xie
Liping Hu
Ping Xu
Xianbin Guo
Junxiu Cai
Min Pan
Jie Tang
Qingtao Gong
Rong Su
Yake Lou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1470373

195 views

Original Research

Published on 03 Apr 2025

Anticoagulation quality with warfarin therapy, and associated factors among adult outpatients at public hospitals in nekemte town, western Ethiopia: a retrospective study

in Drugs Outcomes Research and Policies

Firafan Shuma Teka
Ayana Tadesse Korsa
Habte Gebeyehu Bayisa
Dechasa Befikadu W/Senbat
Refisa Shifera Beyene
Dinka Dugassa Iticha
Birbirsa Sefera Senbeta

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544957

306 views