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CASE REPORT article

Front. Pediatr.
Sec. Pediatric Surgery
Volume 12 - 2024 | doi: 10.3389/fped.2024.1457824

Effect of teduglutide, a glucagon-like peptide-2 analog, in eosinophilic enterocolitis: a case report

Provisionally accepted
Shoko Ogawa Shoko Ogawa Ken-Ichiro Konishi Ken-Ichiro Konishi *Kiyoshi Tanaka Kiyoshi Tanaka Hajime Takayasu Hajime Takayasu Yoshimasa Uematsu Yoshimasa Uematsu Takashi Ito Takashi Ito Hiroyuki Takahashi Hiroyuki Takahashi Yusuke Kumamoto Yusuke Kumamoto
  • School of Medicine, Kitasato University, Sagamihara, Japan

The final, formatted version of the article will be published soon.

    We successfully treated a 4-year-old girl with short bowel syndrome and eosinophilic enterocolitis with teduglutide, a glucagon-like peptide-2 analog. Her eosinophilic enterocolitis was cured without relapse, and we were able to increase enteral nutrition. We found that teduglutide had an antiinflammatory effect in this patient with eosinophilic gastrointestinal disease associated with short bowel syndrome. This report is the first to describe use of teduglutide in the treatment of eosinophilic gastrointestinal disease.

    Keywords: glucagon-like peptide-2 analog, Immune effect, Short Bowel Syndrome, Eosinophilic gastrointestinal diseases, Teduglutide

    Received: 01 Jul 2024; Accepted: 20 Sep 2024.

    Copyright: © 2024 Ogawa, Konishi, Tanaka, Takayasu, Uematsu, Ito, Takahashi and Kumamoto. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ken-Ichiro Konishi, School of Medicine, Kitasato University, Sagamihara, Japan

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