AUTHOR=Ogawa Shoko , Konishi Ken-ichiro , Tanaka Kiyoshi , Takayasu Hajime , Uematsu Yoshimasa , Ito Takashi , Takahashi Hiroyuki , Kumamoto Yusuke TITLE=Effect of teduglutide, a glucagon-like peptide-2 analog, in eosinophilic enterocolitis: a case report JOURNAL=Frontiers in Pediatrics VOLUME=12 YEAR=2024 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2024.1457824 DOI=10.3389/fped.2024.1457824 ISSN=2296-2360 ABSTRACT=
We successfully treated a 4-year-old girl with short bowel syndrome and eosinophilic enterocolitis with teduglutide, a glucagon-like peptide-2 analog. Her eosinophilic enterocolitis was cured without relapse, and we were able to increase enteral nutrition. We found that teduglutide had an anti-inflammatory effect in this patient with eosinophilic gastrointestinal disease associated with short bowel syndrome. This report is the first to describe use of teduglutide in the treatment of eosinophilic gastrointestinal disease.