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CASE REPORT article

Front. Pediatr.
Sec. Pediatric Rheumatology
Volume 12 - 2024 | doi: 10.3389/fped.2024.1410400

Catastrophic antiphospholipid syndrome in a pediatric patient after percutaneous treatment of aortic re-coarctation

Provisionally accepted
Iris Paola García Herrera Iris Paola García Herrera *Carlos Canales Robredo Carlos Canales Robredo Magdalena Aboytes Zavala Magdalena Aboytes Zavala Orfanel Sebastian Pineda Arzate Orfanel Sebastian Pineda Arzate Jose Luis Colin Ortiz Jose Luis Colin Ortiz Luis Alberto Aparicio Vera Luis Alberto Aparicio Vera
  • Hospital para el Niño Poblano, Puebla, Mexico

The final, formatted version of the article will be published soon.

    A female patient in middle childhood was diagnosed with coarctation of the aorta at one month of age and underwent a successful cortectomy. At 11 years old, she developed re-coarctation, which was managed through interventional cardiology. Shortly after the procedure, she experienced a sudden and severe clinical decline, presenting with hypoperfusion of the lower extremities, gastrointestinal bleeding, acute kidney injury, and pancreatitis. Multiple thrombotic events were identified, prompting an extensive evaluation for thrombophilia. The patient tested positive for antiphospholipid antibodies and was diagnosed with catastrophic antiphospholipid antibody syndrome (CAPS). An aggressive treatment was initiated, yielding a favorable response following discharge; she made a full recovery and continues to be monitored regularly in cardiology and rheumatology clinics.

    Keywords: antiphospholipid antibody syndrome, Catastrophic antiphospholipid syndrome, Aortic recoarctation, Heart disease, Congenital heart disease. 2

    Received: 01 Apr 2024; Accepted: 20 Nov 2024.

    Copyright: © 2024 García Herrera, Canales Robredo, Aboytes Zavala, Pineda Arzate, Colin Ortiz and Aparicio Vera. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Iris Paola García Herrera, Hospital para el Niño Poblano, Puebla, Mexico

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