AUTHOR=García Herrera Iris Paola , Canales Robredo Carlos , Aboytes Zavala Magdalena , Merayo Chalico Javier , Pineda Arzate Orfanel Sebastian , Colín Ortíz José Luis , Aparicio Vera Luis Alberto TITLE=Case Report: Catastrophic antiphospholipid syndrome in a pediatric patient after percutaneous treatment of aortic re-coarctation JOURNAL=Frontiers in Pediatrics VOLUME=12 YEAR=2024 URL=https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2024.1410400 DOI=10.3389/fped.2024.1410400 ISSN=2296-2360 ABSTRACT=

A female patient in middle childhood was diagnosed with coarctation of the aorta at one month of age and underwent a successful cortectomy. At 11 years old, she developed re-coarctation, which was managed through interventional cardiology. Shortly after the procedure, she experienced a sudden and severe clinical decline, presenting with hypoperfusion of the lower extremities, gastrointestinal bleeding, acute kidney injury, and pancreatitis. Multiple thrombotic events were identified, prompting an extensive evaluation for thrombophilia. The patient tested positive for antiphospholipid antibodies and was diagnosed with catastrophic antiphospholipid antibody syndrome (CAPS). An aggressive treatment was initiated, yielding a favorable response following discharge; she made a full recovery and continues to be monitored regularly in cardiology and rheumatology clinics.