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BRIEF RESEARCH REPORT article

Front. Pediatr.
Sec. Pediatric Infectious Diseases
Volume 12 - 2024 | doi: 10.3389/fped.2024.1387086

Effectiveness of Pre-Omicron COVID-19 mRNA Vaccines Against Hospitalizations in Infection-Naïve Children: A Case-Control Study

Provisionally accepted
Lung Chang Lung Chang 1,2Ching-Ying Huang Ching-Ying Huang 1,2Nan-Chang Chiu Nan-Chang Chiu 1,2Jin-Yuan Wang Jin-Yuan Wang 1*Hsin Chi Hsin Chi 1,2*Tsung-Ning D. Huang Tsung-Ning D. Huang 1,2*
  • 1 MacKay Children’s Hospital, Taipei, Taiwan
  • 2 Mackay Medical College, New Taipei, Taiwan

The final, formatted version of the article will be published soon.

    This case-control study spanned from July 2022 to September 2023, focusing on the pre-Omicron COVID-19 mRNA vaccines effectiveness against Omicron variant in children without prior SARS-CoV-2 exposure. We reported that pre-Omicron COVID-19 mRNA vaccines significantly reduced Omicron-induced hospitalizations in infection-naïve Taiwanese children. Our study also highlighted the socio-economic factors influencing COVID-19 vulnerability among children population.

    Keywords: COVID-19, Children, Taiwan, Vaccine, effectiveness

    Received: 16 Feb 2024; Accepted: 10 Oct 2024.

    Copyright: © 2024 Chang, Huang, Chiu, Wang, Chi and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Jin-Yuan Wang, MacKay Children’s Hospital, Taipei, Taiwan
    Hsin Chi, MacKay Children’s Hospital, Taipei, Taiwan
    Tsung-Ning D. Huang, MacKay Children’s Hospital, Taipei, Taiwan

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.