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REVIEW article

Front. Oral. Health
Sec. Oral Infections and Microbes
Volume 5 - 2024 | doi: 10.3389/froh.2024.1477004

The Oral Microbiome of Children in Health and Disease -A Literature Review

Provisionally accepted
Salma AlHarbi Salma AlHarbi 1,2Abdullah S. Almushayt Abdullah S. Almushayt 1Shatha O. Bamashmous Shatha O. Bamashmous 3Turki S. Abujamel Turki S. Abujamel 4,5Nada O. Bamashmous Nada O. Bamashmous 1*
  • 1 Pediatric Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia
  • 2 Dental Department, Ministry of Health, Yanbu, Saudi Arabia
  • 3 Department of Periodontology, Faculty of Dentistry, King Abdulaziz University, Jeddah, Makkah, Saudi Arabia
  • 4 Division of Vaccines and Immunotherapy, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah, Makkah, Saudi Arabia
  • 5 Special Infectious Agents Unit, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah, Makkah, Saudi Arabia

The final, formatted version of the article will be published soon.

    The oral microbiome is a complex community of microorganisms residing in the oral cavity interacting with each other and with the host in a state of equilibrium. Disruptions in this balance can result in both oral and systemic conditions. Historically, studying the oral microbiome faced limitations due to culture-dependent techniques that could not capture the complexity and diversity of the microbial community. The emergence of advanced genomic technologies and the ease of sample collection from the oral cavity has revolutionized the understanding of the oral microbiome, providing valuable insights into the bacterial community in both health and disease. This review explores the oral microbiome in children, discussing its formation and dynamics in both states of health and disease, its role in various conditions such as dental caries, periodontal disease, oral cancer, cleft lip and palate, and explores its connection to several systemic consequences.

    Keywords: Children, caries, Dental Plaque, Gingivitis, Periodontitis, oral microbiome, oral cancer

    Received: 06 Aug 2024; Accepted: 02 Oct 2024.

    Copyright: © 2024 AlHarbi, Almushayt, Bamashmous, Abujamel and Bamashmous. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Nada O. Bamashmous, Pediatric Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.