Original Research

Published on 12 Jul 2019

Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection With Transcriptome Analysis

in Pharmacology of Anti-Cancer Drugs

Hanyuan Shen
Zhipeng Qu
Yuka Harata-Lee
Thazin Nwe Aung
Jian Cui
Wei Wang
R. Daniel Kortschak
David L. Adelson

Frontiers in Oncology

doi 10.3389/fonc.2019.00632

5,833 views
23 citations

Review

Published on 10 Jul 2019

Stem Cell Plasticity and Dormancy in the Development of Cancer Therapy Resistance

in Pharmacology of Anti-Cancer Drugs

Maria Laura De Angelis
Federica Francescangeli
Filippo La Torre
Ann Zeuner

Frontiers in Oncology

doi 10.3389/fonc.2019.00626

18,943 views
161 citations

Case Report

Published on 09 Jul 2019

Trabectedin Drug Holiday and Rechallenge in Soft Tissue Sarcomas: Report of 4 Cases and Literature Review

in Pharmacology of Anti-Cancer Drugs

Francesco Pierantoni
Marco Maruzzo
Antonella Brunello
Benedetta Chiusole
Grazia Pusole
Elisabetta Bezzon
Umberto Basso
Vittorina Zagonel

Frontiers in Oncology

doi 10.3389/fonc.2019.00553

4,843 views
4 citations

Original Research

Published on 04 Jul 2019

Folic Acid Receptor-Mediated Targeting Enhances the Cytotoxicity, Efficacy, and Selectivity of Withania somnifera Leaf Extract: In vitro and in vivo Evidence

in Pharmacology of Anti-Cancer Drugs

Yue Yu
Jia Wang
Sunil C. Kaul
Renu Wadhwa
Eijiro Miyako

Frontiers in Oncology

doi 10.3389/fonc.2019.00602

7,472 views
32 citations

Original Research

Published on 04 Jul 2019

Antitumor Effects and Related Mechanisms of Ethyl Acetate Extracts of Polygonum perfoliatum L.

in Pharmacology of Anti-Cancer Drugs

Qinglin Li
Xiaoxuan Fu
Xinyang Ge
Feng Tao
Ping Huang
Minghua Ge
Hongchuan Jin

Frontiers in Oncology

doi 10.3389/fonc.2019.00578

3,923 views
7 citations

Original Research

Published on 03 Jul 2019

Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model

in Pharmacology of Anti-Cancer Drugs

Ingrid R. S. Baliza
Suellen L. R. Silva
Luciano de S. Santos
João H. Araujo Neto
Rosane B. Dias
Caroline B. S. Sales
Clarissa A. Gurgel Rocha
Milena B. P. Soares
Alzir A. Batista
Daniel P. Bezerra

Frontiers in Oncology

doi 10.3389/fonc.2019.00582

3,888 views
19 citations

Original Research

Published on 26 Jun 2019

Rotundic Acid Induces DNA Damage and Cell Death in Hepatocellular Carcinoma Through AKT/mTOR and MAPK Pathways

in Pharmacology of Anti-Cancer Drugs

Gaurab Roy
Su Guan
Hexiang Liu
Lei Zhang

Frontiers in Oncology

doi 10.3389/fonc.2019.00545

4,516 views
18 citations

Review

Published on 21 Jun 2019

Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma

in Pharmacology of Anti-Cancer Drugs

Kaio Murilo Monteiro Espíndola
Roseane Guimarães Ferreira
Luis Eduardo Mosquera Narvaez
Amanda Caroline Rocha Silva Rosario
Agnes Hanna Machado da Silva
Ana Gabrielle Bispo Silva
Ana Paula Oliveira Vieira
Marta Chagas Monteiro

Frontiers in Oncology

doi 10.3389/fonc.2019.00541

42,401 views
375 citations

Original Research

Published on 14 Jun 2019

Ursolic Acid Reverses the Chemoresistance of Breast Cancer Cells to Paclitaxel by Targeting MiRNA-149-5p/MyD88

in Pharmacology of Anti-Cancer Drugs

Fenfen Xiang
Yan Fan
Zhenhua Ni
Qiaoli Liu
Zhaowei Zhu
Zixi Chen
Wenbin Hao
Honghong Yue
Rong Wu
Xiangdong Kang

Frontiers in Oncology

doi 10.3389/fonc.2019.00501

5,213 views
56 citations

Original Research

Published on 13 Jun 2019

Catechins-Modified Selenium-Doped Hydroxyapatite Nanomaterials for Improved Osteosarcoma Therapy Through Generation of Reactive Oxygen Species

in Pharmacology of Anti-Cancer Drugs

Suliman Khan
Muhammad Wajid Ullah
Rabeea Siddique
Yang Liu
Ismat Ullah
Mengzhou Xue
Guang Yang
Hongwei Hou

Frontiers in Oncology

doi 10.3389/fonc.2019.00499

5,494 views
47 citations

Review

Published on 12 Jun 2019

Reversal of Multidrug Resistance in Cancer by Multi-Functional Flavonoids

in Pharmacology of Anti-Cancer Drugs

Qingmei Ye
Kai Liu
Qun Shen
Qingyue Li
Jinghui Hao
Fangxuan Han
Ren-Wang Jiang

Frontiers in Oncology

doi 10.3389/fonc.2019.00487

23,184 views
113 citations

Original Research

Published on 11 Jun 2019

C8-Substituted Imidazotetrazine Analogs Overcome Temozolomide Resistance by Inducing DNA Adducts and DNA Damage

in Pharmacology of Anti-Cancer Drugs

Zhikuan Yang
Danping Wei
Xiaoli Dai
Malcolm F. G. Stevens
Tracey D. Bradshaw
Ying Luo
Jihong Zhang

Frontiers in Oncology

doi 10.3389/fonc.2019.00485

4,466 views
19 citations

Mini Review

Published on 04 Jun 2019

Analysis of Survival Curves: Statistical Methods Accounting for the Presence of Long-Term Survivors

in Pharmacology of Anti-Cancer Drugs

Vera Damuzzo
Laura Agnoletto
Luca Leonardi
Marco Chiumente
Daniele Mengato
Andrea Messori

Frontiers in Oncology

doi 10.3389/fonc.2019.00453

26,640 views
30 citations

Original Research

Published on 04 Jun 2019

CAPE-pNO2 Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway

in Pharmacology of Anti-Cancer Drugs

Qin Huang
Sai Li
Liwen Zhang
Xufang Qiao
Yanyan Zhang
Xiaoyan Zhao
Guojun Xiao
Zhubo Li

Frontiers in Oncology

doi 10.3389/fonc.2019.00461

4,881 views
31 citations

Original Research

Published on 29 May 2019

p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells

in Pharmacology of Anti-Cancer Drugs

Yasamin Dabiri
Mohamed A. Abu el Maaty
Hoi Yin Chan
Jessica Wölker
Ingo Ott
Stefan Wölfl
Xinlai Cheng

Frontiers in Oncology

doi 10.3389/fonc.2019.00438

6,472 views
37 citations

Systematic Review

Published on 29 May 2019

The Efficacy of Different Chemotherapy Regimens for Advanced Biliary Tract Cancer: A Systematic Review and Network Meta-Analysis

in Pharmacology of Anti-Cancer Drugs

Yan Li
Yaoyao Zhou
Yonglan Hong
Meizhi He
Shuyi Wei
Chen Yang
Dayong Zheng
Feiye Liu

Frontiers in Oncology

doi 10.3389/fonc.2019.00441

6,865 views
7 citations

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Articles

Understanding the Mechanistic Contribution of Herbal Extracts in Compound Kushen Injection With Transcriptome Analysis

Stem Cell Plasticity and Dormancy in the Development of Cancer Therapy Resistance

Trabectedin Drug Holiday and Rechallenge in Soft Tissue Sarcomas: Report of 4 Cases and Literature Review

Folic Acid Receptor-Mediated Targeting Enhances the Cytotoxicity, Efficacy, and Selectivity of Withania somnifera Leaf Extract: In vitro and in vivo Evidence

Antitumor Effects and Related Mechanisms of Ethyl Acetate Extracts of Polygonum perfoliatum L.

Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model

Rotundic Acid Induces DNA Damage and Cell Death in Hepatocellular Carcinoma Through AKT/mTOR and MAPK Pathways

Chemical and Pharmacological Aspects of Caffeic Acid and Its Activity in Hepatocarcinoma

Ursolic Acid Reverses the Chemoresistance of Breast Cancer Cells to Paclitaxel by Targeting MiRNA-149-5p/MyD88

Catechins-Modified Selenium-Doped Hydroxyapatite Nanomaterials for Improved Osteosarcoma Therapy Through Generation of Reactive Oxygen Species

Reversal of Multidrug Resistance in Cancer by Multi-Functional Flavonoids

C8-Substituted Imidazotetrazine Analogs Overcome Temozolomide Resistance by Inducing DNA Adducts and DNA Damage

Analysis of Survival Curves: Statistical Methods Accounting for the Presence of Long-Term Survivors

CAPE-pNO2 Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway

p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells

The Efficacy of Different Chemotherapy Regimens for Advanced Biliary Tract Cancer: A Systematic Review and Network Meta-Analysis