Frontiers in Oncology | Cancer Molecular Targets and Therapeutics

Original Research

Published on 11 Jul 2025

Analysis of cancer-associated glycosyltransferases reveals novel targets of non-small cell lung cancer pathogenesis

in Cancer Molecular Targets and Therapeutics

Chang Liu
Thomas van Ee
Jurriaan Janssen
Ernesto Rodríguez
Yongsoo Kim
Teodora Radonic
Victor W. van Beusechem
Marieke F. Fransen
Idris Bahce
Yvette van Kooyk

Frontiers in Oncology

doi 10.3389/fonc.2025.1601368

298 views

Review

Published on 11 Jul 2025

The NLRP3 inflammasome in urogenital cancers: structure, dual function, and therapeutic potential

in Cancer Molecular Targets and Therapeutics

Weiming Sun
Ruiting Ma
Rui Zhao
Jiaju Tian
Wenhui Liu

Frontiers in Oncology

doi 10.3389/fonc.2025.1593774

Systematic Review

Accepted on 10 Jul 2025

Immune Checkpoint Inhibitors in Pancreatic Adenocarcinoma: A Systematic Review and Meta-Analysis of Clinical Outcomes

in Cancer Molecular Targets and Therapeutics

Aisha Al-Khinji
Dhafer Malouche
Noora Al Korbi
Shaikha Al Kuwari
Abdullatif Al Hor

Frontiers in Oncology

doi 10.3389/fonc.2025.1569884

Original Research

Published on 10 Jul 2025

Lamins regulate cancer cell plasticity and chemosensitivity

in Cancer Molecular Targets and Therapeutics

Guofang Chen
Tingyi Wei
Ao Huang
Junwei Shen
Furong Ju
Shichao Huang
Haisen Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1599175

243 views

Case Report

Accepted on 09 Jul 2025

A rare case of ALK-KIF5B gene fusion benefited from treatment with lorlatinib

in Cancer Molecular Targets and Therapeutics

Yuxi Luo
Ouyang Weiwei

Frontiers in Oncology

doi 10.3389/fonc.2025.1594072

Review

Accepted on 09 Jul 2025

Copper metabolism and cuproptosis: Broad perspectives in the treatment of hepatocellular carcinoma

in Cancer Molecular Targets and Therapeutics

Jiale Liang
Ruting Wang
Hongxi Wu
Zhenjin Huang
Ruohan Zhang
Feng Jiang

Frontiers in Oncology

doi 10.3389/fonc.2025.1555858

Editorial

Published on 08 Jul 2025

Editorial: Advancements in drug development: exploring bi-specific antibodies as promising therapeutic strategies in oncology

in Cancer Molecular Targets and Therapeutics

Urs M. Weber
Julie M. Bailis
Angela Coxon
Sharon R. Pine
Giuseppe Giaccone

Frontiers in Oncology

doi 10.3389/fonc.2025.1651944

237 views

Review

Accepted on 07 Jul 2025

Small-molecule and peptide inhibitors of m6A regulatorsAn overview of m6A methylation regulatory factor inhibitors for malignant tumors

in Cancer Molecular Targets and Therapeutics

Xiaocui Liu
Xuefeng Kan

Frontiers in Oncology

doi 10.3389/fonc.2025.1629864

107 views

Original Research

Accepted on 07 Jul 2025

Ansofaxine Hydrochloride inhibits hepatocellular carcinoma growth and enhances targeted therapy through the EGFR/MAPK pathway

in Cancer Molecular Targets and Therapeutics

Yongfei He
Qiang Tao
Shutian Mo
Meifeng Chen
Jicai Wang
Hang Zhai
Shengjie Hong
Qiang Gao
Guangquan Zhang
Chuangye Han

Frontiers in Oncology

doi 10.3389/fonc.2025.1523570

124 views

Review

Accepted on 07 Jul 2025

SLFN11: A Pan-Cancer Biomarker for DNA-Targeted Drugs Sensitivity and Therapeutic Strategy Guidance

in Cancer Molecular Targets and Therapeutics

Kunzhong Zhou
Weifang Wang
Yilin Chen
LI Zhuang

Frontiers in Oncology

doi 10.3389/fonc.2025.1582738

Systematic Review

Published on 07 Jul 2025

Prognostic and clinicopathological value of dbc1 expression in human cancers: a systematic review and meta-analysis

in Cancer Molecular Targets and Therapeutics

Haojia Wang
Xinhong Cheng
Bruce Xianzhuo Zhang
Yong Wang
Shuo Gao
Fanghui Ding
Xiaojing Song
Dandan Li
Haixu Ni
Yang Luo

Frontiers in Oncology

doi 10.3389/fonc.2025.1584622

234 views

Original Research

Published on 07 Jul 2025

High expression of SOX9 is a diagnostic and prognostic indicator of glioma

in Cancer Molecular Targets and Therapeutics

Libo Xu
Zhenhao Wang
Mao Li
Qingsong Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1531937

293 views

Systematic Review

Accepted on 03 Jul 2025

Umbrella Review of Photodynamic Therapy for Cancer: Efficacy, Safety, and Clinical Applications

in Cancer Molecular Targets and Therapeutics

Hanhan Chen
Honglin Li
Hui-jie Li
Zhen Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1528314

155 views

Case Report

Published on 03 Jul 2025

Severe hypotension induced by Almonertinib: a case report with literature review and clinical insights

in Cancer Molecular Targets and Therapeutics

Haiyu Niu
Feixue Song
Xiaochun Zhou
Qiaoying Jin
Yating Liu
Benxin Luo
Hanwen Wei

Frontiers in Oncology

doi 10.3389/fonc.2025.1566768

360 views

Review

Published on 02 Jul 2025

USP39: a key regulator in malignant tumor progression

in Cancer Molecular Targets and Therapeutics

Junyan Li
Jinghua Zhong
Jianming Ye
Yi Xiang
Xiangcai Wang

Frontiers in Oncology

doi 10.3389/fonc.2025.1556011

341 views

Correction

Published on 02 Jul 2025

Correction: FGFR3-TACC3 fusion gene promotes glioblastoma malignant progression through the activation of STAT3 signaling pathway

in Cancer Molecular Targets and Therapeutics

Yiming Li
Jianshen Liang
Xiude Ren
Jiahe Guo
Xisen Wang
Xuya Wang
Shengping Yu
Tao Li
Xuejun Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1637363

423 views