Frontiers in Oncology | Cancer Molecular Targets and Therapeutics

Original Research

Accepted on 16 Jan 2025

Evaluation of patient immunocompetence for immune checkpoint inhibitor therapy using the psoas muscle index: a retrospective cohort study

in Cancer Molecular Targets and Therapeutics

Toshiaki Tsurui
Kazuyuki Hamada
Emiko Mura
Risako Suzuki
Nana Iriguchi
Tomoyuki Ishiguro
Yuya Hirasawa
Ryotaro Ohkuma
Masahiro Shimokawa
Hirotsugu Ariizumi

Frontiers in Oncology

doi 10.3389/fonc.2025.1499650

Mini Review

Accepted on 16 Jan 2025

DNA Methylation and Immune Evasion in Triple-Negative Breast Cancer: Challenges and Therapeutic Opportunities

in Cancer Molecular Targets and Therapeutics

Wen-yu Cai
Xin-Xian Cai
Yi-Ran Fei
Rui Ye
Ding-ming Song
Dan Hu
Wan- Wan Zhang
Ming-Fei Xia
Xiao-Xiao Yang

Frontiers in Oncology

doi 10.3389/fonc.2025.1534055

Original Research

Published on 16 Jan 2025

Predicting recurrence of non-muscle invasive bladder urothelial carcinoma: predictive value of the optimal cut-off value of Ki67

in Cancer Molecular Targets and Therapeutics

Rende Peng
Yaoyu Zhang
Mingzhu Jia
Xinping Yi
Xiaoyao Yi
Shadan Li
Jiangchuan Pi
Wenjun Meng

Frontiers in Oncology

doi 10.3389/fonc.2024.1522009

298 views

Original Research

Published on 16 Jan 2025

Implication of fibroblast growth factor 7 in ovarian cancer metastases and patient survival

in Cancer Molecular Targets and Therapeutics

Laura F. Mortan
Brooke A. Meelheim
Justin Garland
Jacqueline A. Bohn
Zitha Redempta Isingizwe
Doris M. Benbrook

Frontiers in Oncology

doi 10.3389/fonc.2024.1524606

407 views

Case Report

Published on 15 Jan 2025

Case report: Selpercatinib in the treatment of RET fusion-positive advanced lung adenocarcinoma: a challenging clinical case

in Cancer Molecular Targets and Therapeutics

Raffaella Pagliaro
Paola Maria Medusa
Fabiana Vitiello
Luigi Aronne
Susan F. M. Campbell
Fabio Perrotta
Andrea Bianco

Frontiers in Oncology

doi 10.3389/fonc.2024.1500449

420 views

Systematic Review

Published on 15 Jan 2025

First-line treatment for advanced or metastatic EGFR mutation-positive non-squamous non-small cell lung cancer: a network meta-analysis

in Cancer Molecular Targets and Therapeutics

Mengyao Zhang
Lan Sun

Frontiers in Oncology

doi 10.3389/fonc.2024.1498518

431 views

Review

Accepted on 14 Jan 2025

The Role of ESRP1 in Solid Tumor Development through the Regulation of CD44 Splicing and EMT Processes

in Cancer Molecular Targets and Therapeutics

Lili Wang
Min Zhang
Lei Ke Zhao
Xiaohan Yuan
Houyu Zhao
Yanting Liu
Yinghua Ji
Ping Lu

Frontiers in Oncology

doi 10.3389/fonc.2025.1451130

Mini Review

Accepted on 14 Jan 2025

Improving CD3 bispecific antibody therapy in solid tumors using combination strategies

in Cancer Molecular Targets and Therapeutics

Katy Lloyd
Jim Middelburg
Vitalijs Ovcinnikovs
Nora Pencheva
Kristel Kemper
Thorbald van Hall

Frontiers in Oncology

doi 10.3389/fonc.2025.1548446

Original Research

Published on 14 Jan 2025

Efficacy and safety of anlotinib as maintenance treatment in extensive-stage small cell lung cancer: a single-armed single center retrospective study

in Cancer Molecular Targets and Therapeutics

Jin Xiong
Lei Xia

Frontiers in Oncology

doi 10.3389/fonc.2024.1462581

316 views

Systematic Review

Accepted on 13 Jan 2025

Exploring the Role of Artificial Intelligence in Chemotherapy Development, Cancer Diagnosis, and Treatment: Present Achievements and Future Outlook

in Cancer Molecular Targets and Therapeutics

Bassam Abdul
Ali Haider Mohammed
Souheil Hallit
Diana Malaeb
Hassan Hosseini

Frontiers in Oncology

doi 10.3389/fonc.2025.1475893

Case Report

Accepted on 13 Jan 2025

A rare case of vision loss caused by leptomeningeal metastasis of lung adenocarcinoma: a case report and literature review

in Cancer Molecular Targets and Therapeutics

Zhihua LI
Jian Chu
Wennan Shen
Junnan Chen
Yuemei Dong
Manze Zhang
Nan Zhao
Wei Zhao
Haoran Zha
Yalin Han

Frontiers in Oncology

doi 10.3389/fonc.2025.1484383

Original Research

Published on 09 Jan 2025

Rational strategies for designing next-generation oncolytic viruses based on transcriptome analysis of tumor cells infected with oncolytic herpes simplex virus-1

in Cancer Molecular Targets and Therapeutics

Naeme Javid
Shahriyar Abdoli
Majid Shahbazi

Frontiers in Oncology

doi 10.3389/fonc.2024.1469511

376 views

Original Research

Published on 09 Jan 2025

Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways

in Cancer Molecular Targets and Therapeutics

Yu Zhang
Hailong Lun
Naiqiang Zhu
Ning Yang
Kaikai Ding
Bin Chen
Chengbing Chang
Haipeng Gu
Yanqi Liu

Frontiers in Oncology

doi 10.3389/fonc.2024.1485605

498 views

Review

Published on 09 Jan 2025

Key considerations based on pharmacokinetic/pharmacodynamic in the design of antibody-drug conjugates

in Cancer Molecular Targets and Therapeutics

Yangyang Gao
Yuwei Xia
Yixin Chen
Shiqi Zhou
Yingying Fang
Jieru Yu
Leyin Zhang
Leitao Sun

Frontiers in Oncology

doi 10.3389/fonc.2024.1459368

664 views

Original Research

Published on 07 Jan 2025

Machine learning-based identification of proteomic markers in colorectal cancer using UK Biobank data

in Cancer Molecular Targets and Therapeutics

Swarnima Kollampallath Radhakrishnan
Dipanwita Nath
Dominic Russ
Laura Bravo Merodio
Priyani Lad
Folakemi Kola Daisi
Animesh Acharjee

Frontiers in Oncology

doi 10.3389/fonc.2024.1505675

1,221 views

Systematic review

Published on 07 Jan 2025

Efficacy and safety of nivolumab plus ipilimumab in gastrointestinal cancers: a systematic review and meta-analysis

in Cancer Molecular Targets and Therapeutics

Bowen Dai
Jiaping Jiang
Xiaoyu Yu
Haihua Zhan
Zhengchuan Hu

Frontiers in Oncology

doi 10.3389/fonc.2024.1515992

361 views

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Articles

Evaluation of patient immunocompetence for immune checkpoint inhibitor therapy using the psoas muscle index: a retrospective cohort study

DNA Methylation and Immune Evasion in Triple-Negative Breast Cancer: Challenges and Therapeutic Opportunities

Predicting recurrence of non-muscle invasive bladder urothelial carcinoma: predictive value of the optimal cut-off value of Ki67

Implication of fibroblast growth factor 7 in ovarian cancer metastases and patient survival

Case report: Selpercatinib in the treatment of RET fusion-positive advanced lung adenocarcinoma: a challenging clinical case

First-line treatment for advanced or metastatic EGFR mutation-positive non-squamous non-small cell lung cancer: a network meta-analysis

The Role of ESRP1 in Solid Tumor Development through the Regulation of CD44 Splicing and EMT Processes

Improving CD3 bispecific antibody therapy in solid tumors using combination strategies

Efficacy and safety of anlotinib as maintenance treatment in extensive-stage small cell lung cancer: a single-armed single center retrospective study

Exploring the Role of Artificial Intelligence in Chemotherapy Development, Cancer Diagnosis, and Treatment: Present Achievements and Future Outlook

A rare case of vision loss caused by leptomeningeal metastasis of lung adenocarcinoma: a case report and literature review

Rational strategies for designing next-generation oncolytic viruses based on transcriptome analysis of tumor cells infected with oncolytic herpes simplex virus-1

Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways

Key considerations based on pharmacokinetic/pharmacodynamic in the design of antibody-drug conjugates

Machine learning-based identification of proteomic markers in colorectal cancer using UK Biobank data

Efficacy and safety of nivolumab plus ipilimumab in gastrointestinal cancers: a systematic review and meta-analysis