Frontiers in Oncology | Cancer Genetics

Original Research

Published on 21 Jan 2019

Gene Expression and Methylation Analysis in Melanomas and Melanocytes From the Same Patient: Loss of NPM2 Expression Is a Potential Immunohistochemical Marker for Melanoma

in Cancer Genetics

Susumu Fujiwara
Hiroshi Nagai
Haruki Jimbo
Naoe Jimbo
Tomoyo Tanaka
Masukazu Inoie
Chikako Nishigori

Frontiers in Oncology

doi 10.3389/fonc.2018.00675

4,891 views
19 citations

Original Research

Published on 04 Jan 2019

Pathway Instability Is an Effective New Mutation-Based Type of Cancer Biomarkers

in Cancer Genetics

Marianna A. Zolotovskaia
Maxim I. Sorokin
Sergey A. Roumiantsev
Nikolay M. Borisov
Anton A. Buzdin

Frontiers in Oncology

doi 10.3389/fonc.2018.00658

5,321 views
33 citations

Original Research

Published on 04 Jan 2019

The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma

in Cancer Genetics

Xiaobei Zhao
Paul Little
Alan P. Hoyle
Guillaume J. Pegna
Michele C. Hayward
Anastasia Ivanova
Joel S. Parker
David L. Marron
Matthew G. Soloway
Heejoon Jo

Frontiers in Oncology

doi 10.3389/fonc.2018.00584

6,426 views
16 citations

Original Research

Published on 04 Dec 2018

Contribution of MUTYH Variants to Male Breast Cancer Risk: Results From a Multicenter Study in Italy

in Cancer Genetics

Piera Rizzolo
Valentina Silvestri
Agostino Bucalo
Veronica Zelli
Virginia Valentini
Irene Catucci
Ines Zanna
Giovanna Masala
Simonetta Bianchi
Alessandro Mauro Spinelli

Frontiers in Oncology

doi 10.3389/fonc.2018.00583

8,169 views
25 citations

Review

Published on 20 Nov 2018

Defective Nuclear Lamina in Aneuploidy and Carcinogenesis

in Cancer Genetics

Elizabeth R. Smith
Callinice D. Capo-chichi
Xiang-Xi Xu

Frontiers in Oncology

doi 10.3389/fonc.2018.00529

6,993 views
34 citations

Data Report

Published on 31 Oct 2018

GEMO, a National Resource to Study Genetic Modifiers of Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Pathogenic Variant Carriers

in Cancer Genetics

Fabienne Lesueur
Noura Mebirouk
Yue Jiao
Laure Barjhoux
Muriel Belotti
Maïté Laurent
Mélanie Léone
Claude Houdayer
Brigitte Bressac-de Paillerets
Dominique Vaur

Frontiers in Oncology

doi 10.3389/fonc.2018.00490

6,214 views
14 citations

Original Research

Published on 26 Sep 2018

Association Between Genetic Variant in the Promoter of Pri-miR-34b/c and Risk of Glioma

in Cancer Genetics

Jinghui Li
Xiaoyu Liu
Yu Qiao
Renli Qi
Shunjin Liu
Jing Guo
Yang Gui
Juanjuan Li
Hualin Yu

Frontiers in Oncology

doi 10.3389/fonc.2018.00413

2,001 views
4 citations

Review

Published on 26 Sep 2018

The Krebs Cycle Connection: Reciprocal Influence Between Alternative Splicing Programs and Cell Metabolism

in Cancer Genetics

Giuseppe Biamonti
Lucia Maita
Alessandra Montecucco

Frontiers in Oncology

doi 10.3389/fonc.2018.00408

8,682 views
16 citations

Original Research

Published on 11 Sep 2018

Prognostic Genes of Breast Cancer Identified by Gene Co-expression Network Analysis

in Cancer Genetics

Jianing Tang
Deguang Kong
Qiuxia Cui
Kun Wang
Dan Zhang
Yan Gong
Gaosong Wu

Frontiers in Oncology

doi 10.3389/fonc.2018.00374

27,269 views
209 citations

Original Research

Published on 21 Aug 2018

BRCA1 and BRCA2 Mutations Other Than the Founder Alleles Among Ashkenazi Jewish in the Population of Argentina

in Cancer Genetics

Angela R. Solano
Natalia C. Liria
Fernanda S. Jalil
Daniela M. Faggionato
Pablo G. Mele
Alejandra Mampel
Florencia C. Cardoso
Ernesto J. Podesta

Frontiers in Oncology

doi 10.3389/fonc.2018.00323

8,985 views
15 citations

Original Research

Published on 21 Aug 2018

Incidence of Pathogenic Variants in Those With a Family History of Pancreatic Cancer

in Cancer Genetics

Sarah K. Macklin
Pashtoon M. Kasi
Jessica L. Jackson
Stephanie L. Hines

Frontiers in Oncology

doi 10.3389/fonc.2018.00330

3,607 views
4 citations

Original Research

Published on 27 Jul 2018

Quantitative Analysis of BRCA1 and BRCA2 Germline Splicing Variants Using a Novel RNA-Massively Parallel Sequencing Assay

in Cancer Genetics

Suzette Farber-Katz
Vickie Hsuan
Sitao Wu
Tyler Landrith
Huy Vuong
Dong Xu
Bing Li
Jayne Hoo
Stephanie Lam
Sarah Nashed

Frontiers in Oncology

doi 10.3389/fonc.2018.00286

11,344 views
22 citations

Review

Published on 25 May 2018

Multimodal Light Microscopy Approaches to Reveal Structural and Functional Properties of Promyelocytic Leukemia Nuclear Bodies

in Cancer Genetics

Christian Hoischen
Shamci Monajembashi
Klaus Weisshart
Peter Hemmerich

Frontiers in Oncology

doi 10.3389/fonc.2018.00125

8,918 views
34 citations

Original Research

Published on 03 May 2018

Investigation of Experimental Factors That Underlie BRCA1/2 mRNA Isoform Expression Variation: Recommendations for Utilizing Targeted RNA Sequencing to Evaluate Potential Spliceogenic Variants

in Cancer Genetics

Vanessa L. Lattimore
John F. Pearson
Margaret J. Currie
Amanda B. Spurdle
kConFab Investigators
Bridget A. Robinson
Logan C. Walker

Frontiers in Oncology

doi 10.3389/fonc.2018.00140

5,959 views
7 citations

Hypothesis and Theory

Published on 07 Dec 2017

Domesticating Cancer: An Evolutionary Strategy in the War on Cancer

in Cancer Genetics

Gustav van Niekerk
Theo Nell
Anna-Mart Engelbrecht

Frontiers in Oncology

doi 10.3389/fonc.2017.00304

2,896 views
4 citations

Hypothesis and Theory

Published on 14 Sep 2017

An Emergence Framework of Carcinogenesis

in Cancer Genetics

Elizabeth A. W. Sigston
Bryan R. G. Williams

Frontiers in Oncology

doi 10.3389/fonc.2017.00198

12,505 views
27 citations

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Articles

Gene Expression and Methylation Analysis in Melanomas and Melanocytes From the Same Patient: Loss of NPM2 Expression Is a Potential Immunohistochemical Marker for Melanoma

Pathway Instability Is an Effective New Mutation-Based Type of Cancer Biomarkers

The Prognostic Significance of Low-Frequency Somatic Mutations in Metastatic Cutaneous Melanoma

Contribution of MUTYH Variants to Male Breast Cancer Risk: Results From a Multicenter Study in Italy

Defective Nuclear Lamina in Aneuploidy and Carcinogenesis

GEMO, a National Resource to Study Genetic Modifiers of Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Pathogenic Variant Carriers

Association Between Genetic Variant in the Promoter of Pri-miR-34b/c and Risk of Glioma

The Krebs Cycle Connection: Reciprocal Influence Between Alternative Splicing Programs and Cell Metabolism

Prognostic Genes of Breast Cancer Identified by Gene Co-expression Network Analysis

BRCA1 and BRCA2 Mutations Other Than the Founder Alleles Among Ashkenazi Jewish in the Population of Argentina

Incidence of Pathogenic Variants in Those With a Family History of Pancreatic Cancer

Quantitative Analysis of BRCA1 and BRCA2 Germline Splicing Variants Using a Novel RNA-Massively Parallel Sequencing Assay

Multimodal Light Microscopy Approaches to Reveal Structural and Functional Properties of Promyelocytic Leukemia Nuclear Bodies

Investigation of Experimental Factors That Underlie BRCA1/2 mRNA Isoform Expression Variation: Recommendations for Utilizing Targeted RNA Sequencing to Evaluate Potential Spliceogenic Variants

Domesticating Cancer: An Evolutionary Strategy in the War on Cancer

An Emergence Framework of Carcinogenesis