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Original Research

Published on 11 Sep 2023

VNLG-152R and its deuterated analogs potently inhibit/repress triple/quadruple negative breast cancer of diverse racial origins in vitro and in vivo by upregulating E3 Ligase Synoviolin 1 (SYVN1) and inducing proteasomal degradation of MNK1/2

in Breast Cancer

  • Retheesh S. Thankan
  • Elizabeth Thomas
  • Puranik Purushottamachar
  • David J. Weber
  • Vidya P. Ramamurthy
  • Weiliang Huang
  • Maureen A. Kane
  • Vincent C. O. Njar
VNLG-152R and its deuterated analogs potently inhibit/repress triple/quadruple negative breast cancer of diverse racial origins in vitro and in vivo by upregulating E3 Ligase Synoviolin 1 (SYVN1) and inducing proteasomal degradation of MNK1/2
Frontiers in Oncology
doi 10.3389/fonc.2023.1240996
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  • 1 citation