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ORIGINAL RESEARCH article
Front. Oncol.
Sec. Cancer Imaging and Image-directed Interventions
Volume 15 - 2025 | doi: 10.3389/fonc.2025.1508525
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Objective: To explore the application of a deep learning model based on lateral nasopharyngeal X-rays in diagnosing tonsillar and adenoid hypertrophy.Methods: A retrospective study was conducted using DICOM images of lateral nasopharyngeal X-rays from pediatric outpatients aged 2-12 at our hospital from July 2014 to July 2024. The study included patients exhibiting varying degrees of respiratory obstruction symptoms (disease group). Initially, 1006 images were collected, but after excluding low-quality images and standardizing the imaging phase, 819 images remained. These images were divided into training and validation sets in an 8:2 ratio.The independent test set is consisted of 484 images.We delineated the target areas for tonsils and adenoids and used a YOLOv8n-based model for object detection and use various convolutional neural network models to classify the cropped images, assessing the severity of tonsillar and adenoid hypertrophy.We compared the performance of these models on the training and validation sets using metrics such as ROC-AUC, accuracy, precision, recall, and F1 score.The combined model, incorporating YOLOv8 for object detection and secondary classification, demonstrated excellent performance in diagnosing tonsillar and adenoid hypertrophy, significantly improving diagnostic accuracy and consistency. The ResNet18 model, due to its lightweight nature and minimal computational resource requirements, performed exceptionally well in the YOLOv8-ResNet fusion model for detecting and classifying tonsils and adenoids, making it our preferred model.The deep learning model combining YOLOv8n and ResNet18 based on lateral nasopharyngeal X-rays demonstrates significant advantages in diagnosing pediatric tonsillar and adenoid hypertrophy.
Keywords: Tonsillar, Adenoid, Artificial intelligence in medicine, Resnet18, YOLOv8, Diagnostic Imaging
Received: 14 Oct 2024; Accepted: 20 Feb 2025.
Copyright: © 2025 Wu, Zhuo, Yang, Liu, Wu and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jian Wang, Children's Hospital of Soochow University, Suzhou, 215003, Jiangsu Province, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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