Reham Kaifi ^*

• College of Applied Medical Sciences-Jeddah, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia

Brain tumors are characterized by abnormal cell growth within or around the brain, posing severe health risks often associated with high mortality rates. Various imaging techniques, including magnetic resonance imaging (MRI), are commonly employed to visualize the brain and identify malignant growths.Computer-aided diagnosis tools (CAD) utilizing Convolutional Neural Networks (CNNs) have proven effective in feature extraction and predictive analysis across diverse medical imaging modalities. This study explores a CNN trained and evaluated with nine activation functions, encompassing eight established ones from the literature and a modified version of the soft sign activation function. The latter demonstrates notable efficacy in discriminating between four types of brain tumors in MR images, achieving an accuracy of 97.6%. The sensitivity for glioma is 93.7%; for meningioma, it is 97.4%; for cases with no tumor, it is 98.8%; and for pituitary tumors, it reaches 100%. In this manuscript, we propose an advanced CNN architecture that integrates a newly developed activation function. Our extensive experimentation and analysis showcase the model's remarkable ability to precisely distinguish between different types of brain tumors within a substantial and diverse dataset. The findings from our study suggest that this model could serve as an invaluable supplementary tool for healthcare practitioners, including specialized medical professionals and resident physicians, in the accurate diagnosis of brain tumors.