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ORIGINAL RESEARCH article
Front. Nutr.
Sec. Nutritional Epidemiology
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1590137
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Background and Objectives: Malnutrition is a common problem among cancer patients, significantly impacting clinical outcomes and quality of life. This study aimed to evaluate the prevalence of malnutrition and its associated factors in geriatric cancer patients undergoing chemotherapy.This prospective study included 471 patients aged 65 years and older, conducted at Ankara Etlik City Hospital between January and December 2023. Patients' demographic, clinical, and nutritional statuses were assessed using the Mini Nutritional Assessment (MNA). Nutritional status was classified as normal (MNA ≥24), at risk of malnutrition (MNA 17-23.5), and malnourished (MNA <17). Depression and insomnia were evaluated using the Geriatric Depression Scale (GDS) and the Insomnia Severity Index (ISI), respectively. Factors associated with malnutrition were analyzed statistically.Results: Malnutrition was identified in 20.5% of the patients. Malnutrition was significantly associated with radiotherapy (p=0.001), surgical history (p=0.001), adjuvant therapy (p=0.002), metastatic disease (p=0.011), low BMI (p<0.001), high depression scores (p<0.001), moderate-to-severe insomnia (p<0.001), and the presence of comorbidities (p=0.022). However, no significant association was found between pain and malnutrition (p=0.07).This study highlights the multifactorial nature of malnutrition in geriatric cancer patients and emphasizes the importance of regular nutritional assessments using validated tools like MNA. Early detection and intervention can improve clinical outcomes and quality of life. However, the study has certain limitations, including being single-center, the use of self-reported measures, and the exclusion of palliative patients, which may affect the generalizability of the results.
Keywords: Malnutrition, Geriatrics, Depression, Mini nutritional assessment, Cancer
Received: 11 Mar 2025; Accepted: 01 Apr 2025.
Copyright: © 2025 Dogan, Şahinli and yazılıtas. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Ozlem Dogan, Adiyaman University Training and Research hospital, adiyaman, Türkiye
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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