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ORIGINAL RESEARCH article
Front. Nutr.
Sec. Nutrition and Metabolism
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1564549
This article is part of the Research Topic Deciphering Microbial Metabolites: Their Impact on Gastrointestinal and Metabolic Health View all 4 articles
Dietary Index for Gut Microbiota and Its Inverse Association with Female Infertility: Evidence from NHANES 2013-2018
Provisionally accepted- Hubei University of Medicine, Shiyan, China
Infertility has become a global health concern, especially as the aging population continues to grow. Previous studies suggest that gut microbiota plays a crucial role in female reproductive health. This study aimed to investigate the association between the Dietary Index for Gut Microbiota (DI-GM) and female infertility.We analyzed data from 8,910 participants aged 20-45 years in the NHANES 2013-2018 cycles. DI-GM scores were calculated based on dietary recall interviews, including 14 foods and nutrients associated with gut health. Female infertility was identified through reproductive health questionnaires. Weighted logistic regression models were used to assess the relationship between DI-GM and infertility, with adjustments for demographic, lifestyle, and health-related covariates. Restricted cubic
Keywords: DI-GM, Infertility, Dietary Index for Gut Microbiota, NHANES, dietary
Received: 21 Jan 2025; Accepted: 20 Mar 2025.
Copyright: © 2025 cheng, xi, zhou, ouyang, zhao, li, liu and Xia. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Gao Xia, Hubei University of Medicine, Shiyan, China
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