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ORIGINAL RESEARCH article
Front. Nutr.
Sec. Clinical Nutrition
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1562258
This article is part of the Research Topic FODMAPs: Advances in Research and Clinical Practice View all articles
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Objective: To examine the potential association between dietary index of gut microbiota (DI-GM) scores and constipation in adult women in the United States.This cross-sectional study used data from adult participants in the 2005-2010 U.S. National Health Survey (NHANES). Multivariate logistic regression models were used to determine the odds ratios (OR) and 95% confidence intervals (CI) for the association between DI-GM and constipation. Subgroup analyses were also performed to examine the possible interactions between DI-GM and constipation.Results: Of the 7325 subjects, 887 reported constipations, with a prevalence of 12.1%. After adjustment for multivariate modeling, the DI-GM score was significantly associated with constipation (0.92 [95% CI 0.87~ 0.96]; P = 0.001).Similar results were found for the association of beneficial gut microbiota score with constipation (OR 0.89 [95% CI 0.84 to 0.95]; P = 0. 001). Subgroup analyses revealed that the relationship between DI-GM scores and constipation remained stable (P >0.05). Conclusions: DI-GM was negatively associated with the incidence of constipation in the female population. Clinicians should consider the influence of dietary structure on the treatment of constipation in women. Dietary intervention can be an important strategy for the comprehensive treatment of constipation.
Keywords: female populations, DI-GM, NHANES, Constipation, Gut Microbiota, Dietary index
Received: 17 Jan 2025; Accepted: 14 Mar 2025.
Copyright: © 2025 Lu, Feng, Liu and Ding. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Wangfeng Lu, Shangluo Central Hospital, Shangluo, China
Qi Ding, Shangluo Central Hospital, Shangluo, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
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