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REVIEW article
Front. Nutr.
Sec. Clinical Nutrition
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1546089
Parenteral nutritional support in surgical patients: expert consensus statements regarding intravenous lipid emulsions containing omega-3 fatty acids
Provisionally accepted
Robert Martindale 1
David Evans 2
Dan Waitzberg 3
Malissa Warren 1 Manpreet S Mundi 4 Stanislaw Klek 5
Paul Wischmeyer 6
Martin Rosenthal 7*- 1 Oregon Health and Science University, Portland, Oregon, United States
- 2 OhioHealth, Columbus, Ohio, United States
- 3 University of São Paulo, São Paulo, Rio Grande do Sul, Brazil
- 4 Mayo Clinic, Rochester, Minnesota, United States
- 5 Department of Radiotherapy, Maria Sklodowska Curie Institute of Oncology, Warsaw, Masovian, Poland
- 6 Duke University Hospital, Durham, North Carolina, United States
- 7 College of Medicine, University of Florida, Gainesville, Florida, United States
The International Lipids in Parenteral Nutrition (PN) Summit was convened to offer practical guidance and expert consensus opinion regarding the use of intravenous lipid emulsions (ILEs) in various clinical settings. Herein, we briefly review aspects from this summit that are of particular importance for surgical/hospitalized patients.Summit participants identified and discussed new evidence, data, and analyses, that potentially influence the benefits and risks of ILEs in PN or their use in clinical practice. The summit meeting consisted of expert presentations that assessed recent clinical data and best practice, followed by periodic panel discussions to formulate consensus statements.Consensus statements were voted on, anonymously, by the meeting attendees.This review briefly summarizes the rationale for considering ILE choice as a central component of any PN strategy for surgical/hospitalized patients. Thereafter, special patient populations are considered, such as surgery-related intestinal failure, major trauma, and those with chronic critical illnesses. Expert consensus statements are also provided to help bridge the gaps between evidence and clinical practice, hence complementing formal PN societal guideline recommendations.The choice of ILE in PN, particularly those containing fish oil, can play a vital role in improving outcomes for surgical patients.
Keywords: consensus, fish oil, guidelines, Lipids, Omega-3 fatty Acids, Parenteral Nutrition, Surgery
Received: 16 Dec 2024; Accepted: 05 Feb 2025.
Copyright: © 2025 Martindale, Evans, Waitzberg, Warren, Mundi, Klek, Wischmeyer and Rosenthal. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Martin Rosenthal, College of Medicine, University of Florida, Gainesville, 32610, Florida, United States
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