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REVIEW article
Front. Nutr.
Sec. Nutrition, Psychology and Brain Health
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1545951
This article is part of the Research Topic Unlocking the Secrets to Healthy Brain Aging: Diet, Nutritional Bioactive Compounds, and Lifestyle View all articles
Bibliometric analysis and description of research trends on nutritional management in Alzheimer's disease patients (1988-2024)
Provisionally accepted- First Hospital, Peking University, Beijing, China
Background: Alzheimer's disease (AD) is a severe neurodegenerative disorder.Nutritional management has been recognized as a potential therapeutic approach to mitigate AD progression. This study aimed to analyze the bibliometric characteristics and research trends of publications on nutritional management in AD.A systematic search was conducted on the Web of Science Core Collection database to identify publications related to nutritional management in AD from 1988 to 2024. Bibliometric analysis was performed using VOSviewers (V 1.6.20), CiteSpace (V 6.3.R1) and R 4.3.3.A total of 554 publications from 311 countries led by the USA were identified.The number of publications has increased annually. The most cited article discussed the role of diet in providing antioxidants to combat oxidative stress in neurodegenerative diseases. The University of California system published the most articles, and Rush University had the most international collaborations. These publications came from 3,298 authors, among which Mattson MP had the highest total publications and citations.The Journal of Alzheimer's Disease published the most articles and received the most citations. Keywords analysis revealed evolving trends, with early emphasis on "precursor protein" and later shifts to "dietary restriction", and more recently, "insulin resistance" and "synaptic plasticity". Emerging keywords include "obesity", "cognitive impairment" and "association".This study represents the first summary of research trends in AD nutritional management. Future research is likely to focus on the associations between nutrition, insulin resistance, synaptic plasticity, and cognitive impairment in AD patients. This information provides valuable insights for scholars and practitioners in the field.
Keywords: Bibliometrics, publication, Alzheimer's disease, Nutritional management, Diet
Received: 16 Dec 2024; Accepted: 19 Mar 2025.
Copyright: © 2025 Meng, Li, Wang and Peng. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Qing Peng, First Hospital, Peking University, Beijing, China
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