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REVIEW article
Front. Nutr.
Sec. Sport and Exercise Nutrition
Volume 12 - 2025 |
doi: 10.3389/fnut.2025.1539701
Effects of Propolis Intake on Endurance Exercise and Molecular Signaling Related to Inflammation and Oxidative Stress
Provisionally accepted- 1 Yantai Yuhuangding Hospital, Yantai, China
- 2 Taoranting Community Health Service Center, Beijing, China
- 3 Heilongjiang Shooting, Cycling and Archery Sports Management Center, Republic of China Ministry of Finance, Harbin, Heilongjiang Province, China
Honey bees extract sticky material from the exudates of different plants which transform afterwards to propolis. Propolis from several global locations has been shown to contain a wide variety of polyphenolic chemicals. Recent studies have revealed that propolis possesses antioxidant, anti-inflammatory, and immunomodulatory abilities. In laboratory animal studies, it has been demonstrated that propolis can enhance the functioning of the antioxidant defense system and decrease the activity of nuclear factor-kappa B. As a result, they can effectively alleviate the damage caused by exercise. One of the main flavonoids found in propolis, quercetin, has been demonstrated to enhance muscle mitochondrial biogenesis and exercise capacity. Propolis may aid athletes in preventing oxidative and inflammatory damage to their muscles during exercise and enhance their athletic performance. The goal of the current review was to evaluate how propolis consumption affected the molecular signaling associated with antioxidant/oxidant state, pro/antiinflammatory cytokines, and anaerobic/aerobic endurance.
Keywords: Propolis, inflammatory cytokines, Exercise, Oxidant status, sport performance
Received: 04 Dec 2024; Accepted: 07 Feb 2025.
Copyright: © 2025 Xu, Hu and Qu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Xiaoying Xu, Yantai Yuhuangding Hospital, Yantai, China
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