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ORIGINAL RESEARCH article

Front. Nutr.

Sec. Nutritional Epidemiology

Volume 12 - 2025 | doi: 10.3389/fnut.2025.1536893

Association between novel adiposity parameters and hyperuricemia: A cross-sectional study

Provisionally accepted
baoan Wang baoan Wang Chuncheng Ma Chuncheng Ma Jinhua Wu Jinhua Wu Ze Huang Ze Huang *
  • Jiangmen Wuyi Tranditional Chinese Medicine Hospital, Jiangmen, Guangdong Province, China

The final, formatted version of the article will be published soon.

    Objectives: Body mass index (BMI) is a commonly used parameters to measure obesity, but it cannot well reflect the distribution of body fat, which has limitations in clinical practice. Novel adiposity parameters have emerged as substitution to BMI to assess obesity. This study aimed to comprehensively investigate the association between hyperuricemia and novel adiposity parameters. Methods: We included data from the National Health and Nutrition Examination Survey from 1999-2006. Weighted logistic regression was employed to evaluate the relations between hyperuricemia and novel adiposity parameters, including body roundness index (BRI), weight-adjusted waist index (WWI), a body shape index (ABSI), and conicity index (CoI). To assess the most diagnostic factor for hyperuricemia, the receiver operating characteristic (ROC) curve analysis was employed. The area under the curve (AUC) was used to assess the diagnostic power of each parameter.The study included 24,763 participants, 3,528 of whom were diagnosed with hyperuricemia. Compared with the first quartile (Q1), the fourth quartile's (Q4) BRI, WWI, ABSI and CoI were linked to an increased risk of hyperuricemia (OR: 9.

    Keywords: Cross-sectional study, adiposity parameters, Hyperuricemia, National Health and Nutrition Examination Survey, Body roundness index

    Received: 03 Dec 2024; Accepted: 17 Feb 2025.

    Copyright: © 2025 Wang, Ma, Wu and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ze Huang, Jiangmen Wuyi Tranditional Chinese Medicine Hospital, Jiangmen, 529000, Guangdong Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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