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ORIGINAL RESEARCH article

Front. Nutr.
Sec. Clinical Nutrition
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1523046
This article is part of the Research Topic Nutrition in Pancreatic Diseases: The Role of Nutritional Status and Nutrition Therapy in the Management of Pancreatitis and Pancreatic Cancer View all articles

The value of systemic immunoinflammatory index, nutritional risk index and triglyceride glucose index in predicting the condition and prognosis of patients with hyperlipidemic acute pancreatitis

Provisionally accepted
Yuanzhen Wang Yuanzhen Wang *Yaling Yun Yaling Yun *Ting Ye Ting Ye *Wentun Yao Wentun Yao *Yufeng Guo Yufeng Guo *Liya Huang Liya Huang *
  • General Hospital of Ningxia Medical University, Yinchuan, China

The final, formatted version of the article will be published soon.

    Objective: To investigate the function and prognosis of pancreatitis in patients with hyperlipidemia acute pancreatitis characterized by systemic immunoinflammatory index (SII), nutritional risk index (NRI), and triglyceride glucose index (TyG).Methods: A total of 300 HTGAP patients admitted to the General Hospital of Ningxia Medical University from January 2022 to June 2023 were selected and divided into mild acute pancreatitis group (MAP group), moderate severe acute pancreatitis group (SMAP group) and severe acute pancreatitis group (SAP group) according to their severity. The SII,NRI and TyG indices in the three sets of data were recorded and compared, and the value of SII, NRI and TyG indices in predicting the occurrence of HTGAP was analyzed by receiver operating characteristic (ROC) curve.The SII and TyG indices in SAP group (3259.42795.8, 4.51.1) were higher than those in MSAP group (2563.71614.1, 4.30.8) and MAP group (1991.11566.8, 4.10.8), and the difference was statistically significant (P0.005). ROC curve showed that the AUC of SII,NRI and TyG index combined to predict SAP occurrence was 0.705(95%CI:0.632~0.778).Conclusion: SII,NRI and TyG index are related to the severity of HTGAP disease,and the combination of the three can better predict the occurrence of SAP.

    Keywords: acute pancreatitis, Hyperlipidemia, ystemic immunoinflammatory index, Nutritional risk index, Triglyceride glucose index

    Received: 12 Nov 2024; Accepted: 08 Jan 2025.

    Copyright: © 2025 Wang, Yun, Ye, Yao, Guo and Huang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yuanzhen Wang, General Hospital of Ningxia Medical University, Yinchuan, China
    Yaling Yun, General Hospital of Ningxia Medical University, Yinchuan, China
    Ting Ye, General Hospital of Ningxia Medical University, Yinchuan, China
    Wentun Yao, General Hospital of Ningxia Medical University, Yinchuan, China
    Yufeng Guo, General Hospital of Ningxia Medical University, Yinchuan, China
    Liya Huang, General Hospital of Ningxia Medical University, Yinchuan, China

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