Skip to main content

ORIGINAL RESEARCH article

Front. Nutr.
Sec. Nutritional Epidemiology
Volume 12 - 2025 | doi: 10.3389/fnut.2025.1493792

Association between novel anthropometric indices and overactive bladder: a population-based study

Provisionally accepted
Heng Liu Heng Liu 1Dong Huqiang Dong Huqiang 2Mingchu Jin Mingchu Jin 1Yu Zhou Yu Zhou 1*Haidong Hao Haidong Hao 1*Yutang Yuan Yutang Yuan 1*Hongtao Jia Hongtao Jia 1*
  • 1 Renmin Hospital, Hubei University of Medicine, Shiyan, China
  • 2 Ningxia Medical University, Yinchuan, Ningxia, China

The final, formatted version of the article will be published soon.

    Background: Abdominal obesity is recognized as a key risk factor for developing OAB.However, traditional measures of obesity, such as the waist-to-height ratio (WHtR), waist circumference, and body mass index (BMI), may not sufficiently capture fat distribution in the body. This study aims to evaluate the relationship between novel anthropometric indices and OAB, providing a more accurate assessment of obesityrelated risk factors.The National Health and Nutrition Examination Survey (NHANES) data from 2007-2018 were utilized, comprising 27,560 participants. To assess the association and discriminative ability of novel anthropometric indices, including the Body Roundness Index (BRI), A Body Shape Index (ABSI), Waist-to-Weight Index (WWI), and Relative Fat Mass (RFM), with OAB, we employed multivariable logistic regression, restricted cubic spline (RCS) analysis, subgroup analysis, and receiver operating characteristic (ROC) curve methods.Results: Multivariable logistic regression analysis indicated that higher levels of novel anthropometric indices were positively associated with OAB prevalence. One z-score increase in WWI, BRI, RFM, and ABSI was associated with a 16%, 31%, 57%, and 5% higher likelihood of OAB, respectively. RCS analysis revealed a non-linear relationship between RFM and OAB. ROC analysis indicated that WWI (AUC = 0.680) and RFM (AUC = 0.661) provided better diagnostic accuracy than traditional measures such as BMI (AUC = 0.599). Subgroup analyses supported the robustness of these findings.: Novel anthropometric indices were positively associated with OAB prevalence. WWI and RFM demonstrated significantly better diagnostic value for OAB than BMI and WHtR. Future studies should investigate the potential of combining multiple anthropometric indices to improve predictive accuracy and conduct prospective studies to determine causality.

    Keywords: overactive bladder, WWI, BRI, RFM, ABSi, NHANES

    Received: 09 Sep 2024; Accepted: 06 Jan 2025.

    Copyright: © 2025 Liu, Huqiang, Jin, Zhou, Hao, Yuan and Jia. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yu Zhou, Renmin Hospital, Hubei University of Medicine, Shiyan, China
    Haidong Hao, Renmin Hospital, Hubei University of Medicine, Shiyan, China
    Yutang Yuan, Renmin Hospital, Hubei University of Medicine, Shiyan, China
    Hongtao Jia, Renmin Hospital, Hubei University of Medicine, Shiyan, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.