Skip to main content

ORIGINAL RESEARCH article

Front. Nutr.
Sec. Nutritional Epidemiology
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1521124

Increased intake of marine fish contributed to a decreased odds of comorbid depressive symptoms and coronary heart disease in Chinese adults

Provisionally accepted
Yuncao Fan Yuncao Fan 1Wei Chen Wei Chen 2Wenhui Lin Wenhui Lin 1Jungu Jin Jungu Jin 2Enyu Lou Enyu Lou 2Jiaying Lao Jiaying Lao 2Yu-Hsin Chen Yu-Hsin Chen 2Jianzhi Shao Jianzhi Shao 1Qizeng Wang Qizeng Wang 1Jiang Qingxi Jiang Qingxi 2Fan Wang Fan Wang 3Jinzhong Xu Jinzhong Xu 1Yanlong Liu Yanlong Liu 2*Bo Yang Bo Yang 4*
  • 1 First People's Hospital of Wenling, Wenling, China
  • 2 Wenzhou Medical University, Wenzhou, China
  • 3 Beijing Huilongguan Hospital, Peking University, Beijing, Beijing Municipality, China
  • 4 School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang Province, China

The final, formatted version of the article will be published soon.

    Backgrounds: Increased consumption of fish has beneficial impacts upon emotional health; however, this benefit for comorbid depressive symptoms and coronary heart disease (DCHD) is not fully clear. We aimed to investigate the relationship between consumption of marine fish and DCHD in Chinese adults. Methods: A cross-sectional study was conducted in 1,106 participants aged 25-95 years living in Taizhou, China. Fish intakes were assessed by using a validated food frequency questionnaire, with their tertiles as category levels of ≤ 1 time/week, 2-6 times/week, and ≥ 7 times/week. Coronary heart disease (CHD) was diagnosed using the coronary angiography, while the concurrent depressive symptoms was indicated using ≥ 8 scores from hospital anxiety and depression scales (HADS). Primary measurements were the prevalent DCHD, presented as multivariate-adjusted odds ratios (ORs) with 95% confidence intervals (CIs). Results: A total of 932 participants were included, 88 (9.44%) participants with depressive symptoms, 477 (51.18%) CHD, and 106 (11.37%) DCHD, respectively. Participants at the highest tertile of fish intake have a lower odds of DCHD compared with those at the lowest (OR: 0.34, 95%CI: 0.20, 0.58), with 42% reductions in odds of DCHD for per one-tertile (3 times/week) increase (OR: 0.58, 95% CI: 0.45, 0.76). The beneficial associations were pronounced with decreased odds of depressive symptom (OR: 0.31, 95% CI: 0.20, 0.47), but not with CHD (OR: 0.87, 95% CI: 0.59, 1.29). Conclusions: Increased consumption of marine fish is associated with decreased severity of depressive symptoms, which might have great benefits to-wards comorbid depressive symptom and with coronary heart diseases.

    Keywords: fish, Depression, coronary heart disease, Comorbidity, nutrition epidemiology

    Received: 01 Nov 2024; Accepted: 23 Dec 2024.

    Copyright: © 2024 Fan, Chen, Lin, Jin, Lou, Lao, Chen, Shao, Wang, Qingxi, Wang, Xu, Liu and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yanlong Liu, Wenzhou Medical University, Wenzhou, China
    Bo Yang, School of Public Health and Management, Wenzhou Medical University, Wenzhou, 325035, Zhejiang Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.