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ORIGINAL RESEARCH article

Front. Nutr.
Sec. Food Chemistry
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1496306
This article is part of the Research Topic Enhancing the Biological Activity and Applications of Polysaccharides through Modification View all articles

Acid-assisted polysaccharides extracted from Asparagus cochinchinensis protect against Alzheimer's disease by regulating the microbiota-gut-brain axis

Provisionally accepted
Zhiqiang Zhang Zhiqiang Zhang 1*Li Wang Li Wang 2Hui Wang Hui Wang 1
  • 1 Henan University of Chinese Medicine, Zhengzhou, China
  • 2 Henan Agricultural University, Zhengzhou, Henan Province, China

The final, formatted version of the article will be published soon.

    In this study, an acid-assisted extraction strategy was used to extract a novel polysaccharide (ACP) from Asparagus cochinchinensis, after which this polysaccharide was purified and subjected to extensive characterization. ACP was determined to have an average molecular weight of 15,580 Da in structural characterization studies, and it was found to primarily consist of glucose, galactose, L-fucose, and fructose at an 82.14:12.23:2.61:2.49 ratio. Trace amounts of xylose, arabinose, and rhamnose were also detected in ACP preparations at a 0.48:0.04:0.02 ratio. GC-MS analyses identified eight different sugar linkages within ACP, including Glcp-(1→, →2)-Glcp-(1→, →6)-Glcp-(1→, →4)-Glcp-(1→, →3, 4)-Glcp-(1→, →2,4) -Galp-(1→, →4,6)-Galp-(1→, and →3,4,6)-Galp-(1→ linkages present at 23.

    Keywords: polysaccharide, Asparagus cochinchinensis, Microbiota-gut-brain, Identification of structure, Gut Microbiota

    Received: 14 Sep 2024; Accepted: 24 Oct 2024.

    Copyright: © 2024 Zhang, Wang and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Zhiqiang Zhang, Henan University of Chinese Medicine, Zhengzhou, China

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