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ORIGINAL RESEARCH article

Front. Nutr.
Sec. Nutritional Epidemiology
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1486741
This article is part of the Research Topic Construction of Nutrient Delivery System for Carotenoids and Their Antioxidant and Anti-inflammatory Activities View all articles

Association between dietary carotenoids intake and fecal incontinence in American adults: evidence from NAHNES 2005-2010 Author List and Affiliations

Provisionally accepted
Zhigang Li Zhigang Li Zan Wen Zan Wen Fei Cheng Fei Cheng *Jiaqing Cao Jiaqing Cao
  • Nanchang University, Nanchang, China

The final, formatted version of the article will be published soon.

    Carotenoids represent a class of bioactive compounds with potential implications for gut health.However, the relationship between dietary carotenoid intake (DCI) and fecal incontinence (FI) remains unclear. This study aims to elucidate the association between DCI and the risk of FI.Participants aged 20 and above from the National Health and Nutrition Examination Survey (NHANES, 2005(NHANES, -2010) ) were included in the study. Data on FI were derived from the bowel health questionnaire, while DCI information was obtained from dietary interviews. Survey-weighted logistic regression analysis and restricted cubic splines (RCS) were employed to evaluate the relationship between DCI, its subtypes, and FI. Weighted quantile sum (WQS) regression was utilized to assess the overall effect of DCI and its predominant subtypes. Finally, subgroup analyses were conducted.The study included a total of 11,915 participants, of whom 1,023 (7.0%) experienced FI. Logistic regression analysis revealed that, after adjusting for all covariates, there was a significant inverse association between DCI and the risk of FI (Model 2: Q4 vs. Q1, OR=0.67, 95% CI: 0.52-0.86, p=0.003). However, among the DCI subtypes, only β-carotene was found to have a significant inverse relationship with FI (Model 2: Q4 vs. Q1, OR=0.68, 95% CI: 0.52-0.88, p=0.005). The RCS curves indicated no nonlinear relationship between DCI, its subtypes, and FI (all p-nonlinear > 0.05). WQS analysis identified β-carotene (weight 38.2%) and lutein/zeaxanthin (weight 27.8%) as the primary contributors.High levels of carotenoid intake, particularly β-carotene and lutein/zeaxanthin, are associated with a reduced risk of fecal incontinence. This discovery provides dietary recommendations for patients suffering from FI.

    Keywords: dietary carotenoids intake, Fecal Incontinence, NHANES, β-Carotene, Lutein/zeaxanthin

    Received: 26 Aug 2024; Accepted: 28 Oct 2024.

    Copyright: © 2024 Li, Wen, Cheng and Cao. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Fei Cheng, Nanchang University, Nanchang, China

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