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BRIEF RESEARCH REPORT article

Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1477674

INCREASED FAT MASS AND OBESITY RISK AFTER ELEXACAFTOR-TEZACAFTOR-IVACAFTOR THERAPY IN YOUNG ADULTS WITH CYSTIC FIBROSIS

Provisionally accepted
Ana Merino Sánchez-Cañete Ana Merino Sánchez-Cañete 1*Concepción Marina López Cárdenes Concepción Marina López Cárdenes 1Saioa Vicente Santamaría Saioa Vicente Santamaría 1José Ramón Gutiérrez Martínez José Ramón Gutiérrez Martínez 2Marta Suárez González Marta Suárez González 2María Álvarez Merino María Álvarez Merino 2David González Jiménez David González Jiménez 2
  • 1 Ramón y Cajal University Hospital, Madrid, Spain
  • 2 Central University Hospital of Asturias, Oviedo, Spain

The final, formatted version of the article will be published soon.

    We wish to submit an original research article entitled "Increased fat mass and obesity risk after elexacaftor/tezacaftor /ivacaftor therapy in young adults with cystic fibrosis" for consideration by Frontiers in Nutrition We confirm that this work is original and has not been published elsewhere, nor is it currently under consideration for publication elsewhere. In this paper, we show body composition behavior of patients in the first months in treatment with Elexacaftor/Tezacaftor/Ivacaftor using bioelectrical impedance analysis. This is significant because the best of our knowledge, there are currently no studies using bioelectrical impedance analysis to assess body composition in PwCF on Elexacaftor/Tezacaftor/Ivacaftor. We believe that this manuscript is appropriate for publication by Frontiers in Nutrition because it reflects a change in the nutritional management of cystic fibrosis patients in line with the changes in body composition observed in our study. We have no conflicts of interest to disclose.

    Keywords: Bioelectrical impedance (BIA), Nutritional Status, CFTR modulator, Body Composition, Cystic Fibrosis

    Received: 08 Aug 2024; Accepted: 11 Oct 2024.

    Copyright: © 2024 Merino Sánchez-Cañete, López Cárdenes, Vicente Santamaría, Gutiérrez Martínez, Suárez González, Álvarez Merino and González Jiménez. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Ana Merino Sánchez-Cañete, Ramón y Cajal University Hospital, Madrid, Spain

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.