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REVIEW article

Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1475111

Metabolic syndrome therapy in pediatric age -between classic and modern. From diets to pipeline drugs

Provisionally accepted
FRASINARIU OTILIA FRASINARIU OTILIA Vasile Valeriu Lupu Vasile Valeriu Lupu Laura Trandafir Laura Trandafir Violeta Streanga Violeta Streanga *Elena Jechel Elena Jechel *Iris Bararu-Bojan Iris Bararu-Bojan Ioana Vasiliu Ioana Vasiliu Magdalena Cuciureanu Magdalena Cuciureanu Isabela Ioana Loghin Isabela Ioana Loghin Costica Mitrofan Costica Mitrofan Alin Horatiu Nedelcu Alin Horatiu Nedelcu Anton Knieling Anton Knieling Ancuta Lupu Ancuta Lupu
  • Grigore T. Popa University of Medicine and Pharmacy, Iași, Romania

The final, formatted version of the article will be published soon.

    The metabolic syndrome, made up of the sum of the entities that define it (obesity, hypertension, dyslipidemias and non-alcoholic hepatic steatosis) has gained an important place in the research of the last decades. This aspect is mainly due to the complexity of management in pediatric practice. The main directions in his approach therefore bring together the concern of counteracting the noise or systemic, of the multiple intercurrents at the physiopathological level, as well as the negative imprint exerted on the quality of life. Its appearance and evolution are currently controversial topics, but the influence of genetic predisposition and lifestyle (diet, physical activity, psychological balance) are certainties. Considering the escalation of the incident at the global level, it is self-evident that it is necessary to know the pathogenesis and practice countermeasures for prophylactic or therapeutic purposes. The present work aims to summarize general aspects related to the metabolic syndrome encountered in pediatric age, with an emphasis on complementary therapeutic perspectives and their effectiveness, by analyzing the latest data from the specialized literature, accessed with the help of international databases (e.g. PubMed, Web of Science, Scopus, Embase, Google Scholar).

    Keywords: metabolic syndrome, Child, pathophysiology, Complementary Therapies, lifestyle modification, mediterranean diet

    Received: 05 Aug 2024; Accepted: 18 Nov 2024.

    Copyright: © 2024 OTILIA, Lupu, Trandafir, Streanga, Jechel, Bararu-Bojan, Vasiliu, Cuciureanu, Loghin, Mitrofan, Nedelcu, Knieling and Lupu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Violeta Streanga, Grigore T. Popa University of Medicine and Pharmacy, Iași, Romania
    Elena Jechel, Grigore T. Popa University of Medicine and Pharmacy, Iași, Romania

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.