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ORIGINAL RESEARCH article

Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1471737

Correlation Between Fruit Consumption and 10-Year All-Cause Mortality in Patients with Dyslipidemia

Provisionally accepted
Yuanjuan Zheng Yuanjuan Zheng 1*Feifei Sun Feifei Sun 2*Suling Ye Suling Ye 3Zhu Jinzhou Zhu Jinzhou 3Yu Ma Yu Ma 3*Mengmeng Shan Mengmeng Shan 3*Shaomi Li Shaomi Li 3*Yingying Chen Yingying Chen 3*Jie Li Jie Li 3*
  • 1 The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei Province, China
  • 2 Heilongjiang Provincial Corps Hospital of Chinese People’s Armed Police Forces, Harbin, Jilin Province, China
  • 3 Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qinghai, China

The final, formatted version of the article will be published soon.

    Background: Consuming fruit provides health benefits. Reportedly, increased fruit consumption reduces the risks of hypertension and cardiovascular disease. However, existing studies have not clarified the effect of fruit consumption on mortality risk in patients with dyslipidemia. This study aimed to assess the correlation between the consumption of different types of fruits and all-cause mortality in patients with dyslipidemia. Methods: A total of 2,184 patients with dyslipidemia were included in this study, and trends in the correlation between the frequency of consumption of different types of fruits and the 10-year all-cause mortality risk in patients with dyslipidemia were analyzed by smoothed curve fitting, Cox regression, and Kaplan–Meier curve analysis. Subgroup analysis and interaction test were applied to analyze the stability of the effect of apple consumption on 10-year all-cause mortality in patients with dyslipidemia. Results: Smoothed curve fitting and Cox regression analyses revealed a significant reduction in the 10-year all-cause mortality risk in patients with dyslipidemia who consumed apples 3–4 times/week (hazard ratio [HR] = 0.61, 95% confidence interval [CI]: 0.43–0.87, P = 0.007) and in those who consumed bananas 3–4 times/week (HR = 0.71, 95% CI: 0.52–0.98, P = 0.039), with a more pronounced effect in patients who consumed both apples and bananas (HR = 0.55, 95% CI: 0.30–0.99, P = 0.045). Other fruits did not exhibit similar effects. Conclusion: Consuming apples or bananas 3–4 times/week significantly improved the 10-year survival rate in patients with dyslipidemia, and the effect was even more profound in patients who consumed both fruits.

    Keywords: Fruit, apple, Banana, Dyslipidemia, Mortality, NHANES

    Received: 28 Jul 2024; Accepted: 13 Sep 2024.

    Copyright: © 2024 Zheng, Sun, Ye, Jinzhou, Ma, Shan, Li, Chen and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Yuanjuan Zheng, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei Province, China
    Feifei Sun, Heilongjiang Provincial Corps Hospital of Chinese People’s Armed Police Forces, Harbin, Jilin Province, China
    Yu Ma, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qinghai, China
    Mengmeng Shan, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qinghai, China
    Shaomi Li, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qinghai, China
    Yingying Chen, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qinghai, China
    Jie Li, Ruijin-Hainan Hospital Shanghai Jiao Tong University School of Medicine (Hainan Boao Research Hospital), Qinghai, China

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