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ORIGINAL RESEARCH article

Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1467889
This article is part of the Research Topic Foods, Dietary Supplements, and Herbal Products Treating the Diseases of the 21st Century: Moving from Traditional to Scientific Research: Volume II View all 9 articles

Associations of dietary riboflavin intake with coronary heart disease in US adults: a cross-sectional study of NHANES 2007-2018

Provisionally accepted
Qiqi Jin Qiqi Jin Shanjiang Chen Shanjiang Chen Xiaojun Ji Xiaojun Ji *
  • Wenzhou Central Hospital, Wenzhou, China

The final, formatted version of the article will be published soon.

    Objective: There is currently little study on the relationship between dietary riboflavin intake and coronary heart disease (CHD) risk.Methods: Using information from the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2018, we carried out a cross-sectional study.Dietary riboflavin intake and CHD risk were examined using weighted univariate and multivariable logistic regression. To learn more about the connection between dietary riboflavin intake and CHD risk, subgroup analyses and interactions were conducted.Next, the potential non-linear association was visually described using restricted cubic spline (RCS).The risk of CHD was inversely correlated with dietary riboflavin consumption. The multivariable odds ratio (OR) with 95% confidence interval (CI) for the risk of CHD was 0.52 (95%Cl: 0.34-0.81, Ptrend=0.009) for the highest vs. lowest tertiles of riboflavin. This protective effect of dietary riboflavin on CHD was influenced by gender, drinking status and serum folate concentration. A non-linear inverse connection (Pfor nonlinearity ≤ 0.001) was shown using RCS analysis between riboflavin intake and the risk of CHD.Conclusions: Our research suggested that consuming more riboflavin in your diet may lessen the risk of CHD. The results improved the current knowledge base and supplied potential implications for dietary recommendations and health policy.

    Keywords: Riboflavin, coronary heart disease, CHD, National Health and Nutrition Examination, Cross-sectional study

    Received: 21 Jul 2024; Accepted: 26 Nov 2024.

    Copyright: © 2024 Jin, Chen and Ji. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xiaojun Ji, Wenzhou Central Hospital, Wenzhou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.