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ORIGINAL RESEARCH article

Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1456091
This article is part of the Research Topic Assessment of Nutritional Status in Chronic Diseases View all 8 articles

Ability of GLIM and MNA-FF to diagnose malnutrition and predict sarcopenia and frailty in hospitalized adults over 60 years of age

Provisionally accepted
Gabriella D. Silva Gabriella D. Silva 1,2*Afra V. Batista Afra V. Batista 2,3Maria C. Costa Maria C. Costa 1,2ANA CÉLIA OLIVEIRA DOS SANTOS ANA CÉLIA OLIVEIRA DOS SANTOS 1,3*
  • 1 Institute of Biological Sciences, University of Pernambuco, Recife, Pernambuco, Brazil
  • 2 Oswaldo Cruz University Hospital, University of Pernambuco, Recife, Brazil
  • 3 Faculdade de Ciências Médicas, Universidade de Pernambuco, Recife, Brazil

The final, formatted version of the article will be published soon.

    Introduction: Malnutrition remains common in adults over 60 years old. Although there are screening and diagnostic tools for malnutrition, there is no globally used approach to diagnosing malnutrition in older adults admitted to hospital. In this study, we verified the agreement between the Global Leadership Initiative on Malnutrition (GLIM) and the Mini Nutritional Assessment (MNA) and the ability of the instruments to identify frailty and sarcopenia associated with malnutrition. Methods: Adults over 60 years old, malnutrition diagnosis was performed by the Mini Nutritional Assessment Full Form (MNA-FF) tool and by GLIM complete using calf circumference and Fat-Free Mass Index to assess muscle mass, with and without Mini Nutritional Assessment Short Form (MNA-SF) screening. Health conditions were assessed in older adults, and the association of these conditions with malnutrition was analyzed using both tools. Results: A total of 432 adults over 60 years old were investigated with a mean age of 71.14 ±8 years. The GLIM criteria with the nutritional screening tool identified 61-63% of older adults as malnourished. Of these, 63-64% were severely malnourished. The MNA-FF tool classified 20% of those assessed as malnourished. The agreement between MNA-FF and GLIM was K -0.10, -0.11, being better with the use of screening.Sarcopenia was associated with malnutrition by MNA-FF (OR: 3.08, 95% CI: 1.84-5.14) and only by GLIM ANTHRO (OR: 1.66, 95% CI: 1.05-2.63). Frailty was associated with MNA-FF (OR: 15.99, 95% CI: 2.16-118.36), GLIM ANTHRO (OR: 2.21, 95% CI: 1.31-3.71) and GLIM BIA (OR: 2.45, 95% CI: 1.45-4.12). Conclusion: It is possible to verify that divergent conceptual frameworks are used to understand malnutrition by MNA-FF and GLIM, and that the GLIM obtained a greater number of malnutrition diagnoses. Both, the GLIM ANTHRO and the MNA-FF associated malnutrition with frailty and sarcopenia, with higher hazard ratios for the MNA-FF.

    Keywords: Calf circumference, Fat-free mass index (FFMI), GLIM, muscle mass, Nutritional assessment, Nutritional screening

    Received: 28 Jun 2024; Accepted: 17 Oct 2024.

    Copyright: © 2024 Silva, Batista, Costa and DOS SANTOS. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Gabriella D. Silva, Institute of Biological Sciences, University of Pernambuco, Recife, 50.100-130, Pernambuco, Brazil
    ANA CÉLIA OLIVEIRA DOS SANTOS, Institute of Biological Sciences, University of Pernambuco, Recife, 50.100-130, Pernambuco, Brazil

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