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ORIGINAL RESEARCH article

Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1433274
This article is part of the Research Topic Mediterranean Diet for Healthy Aging View all articles

Mediterranean Diet and Atrial Fibrillation: A Case-Control Study from China

Provisionally accepted
Qian Zhang Qian Zhang *Su-Ping Wu Su-Ping Wu Xu Liu Xu Liu Yun-Long Wang Yun-Long Wang
  • Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China

The final, formatted version of the article will be published soon.

    The aim of this study was to assess the association between adherence to Mediterranean diet and the presence of atrial fibrillation (AF) in a Northern Chinese population.This study was a single center, case-control study. A total of 952 low risk participants in Beijing Anzhen Hospital from 2016 to 2021 were collected, including 476 patients with first diagnosed of atrial fibrillation and 476 age and sex matched controls.According to the food frequency questionnaire (FFQ), the alternate Mediterranean diet score (AMED) was calculated, which was 0-9 points，indicating the adherence to the Mediterranean diet from low to high.The average age of the participants was 57.6±9.1 years old, and 70.2% were men.After analyzing every component of AMED, vegetable consumption shows a negative correlation with the risk of AF, whereas alcohol consumption demonstrates a positive correlation with it (OR=0.61, 95% CI 0.44-0.80, P<0.001; OR=1.99, 95% CI 1.48-2.58, P<0.001). All patients were grouped according to AMED score. A significant inverse association between AMED and the risk of AF was observed. Compared with participants with AMED<4, the multivariable-adjusted ORs of AF were 0.75 (95% CI 0.55-1.06) for AMED 4-5 and 0.61 (95% CI 0.43-0.89) for AMED ≥6, with a trend in risk (P=0.008). Results were consistent in stratified analyses of gender, age, BMI and smoking.The Mediterranean diet was inversely associated with the risk of AF in this Northern Chinese population.

    Keywords: cardiovascular disease, Atrial Fibrillation, mediterranean diet, Diet pattern, Arrythmia

    Received: 15 May 2024; Accepted: 21 Oct 2024.

    Copyright: © 2024 Zhang, Wu, Liu and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Qian Zhang, Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.