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ORIGINAL RESEARCH article

Front. Nutr.
Sec. Nutrition and Metabolism
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1428938

Compar ative analysis of the nutr itional composition, digestibility, metabolomics pr ofiles and gr owth influence of cow, goat and sheep milk powder diets in r at models

Provisionally accepted
Chun Yang Chun Yang 1Jiancun Pan Jiancun Pan 2*Shaojie Pang Shaojie Pang 2*Hu Shuang Hu Shuang 1*Miao Liu Miao Liu 1*Xinyan Zhang Xinyan Zhang 2*Liping Song Liping Song 2*Xiangnan Ren Xiangnan Ren 3*Zhongli Wang Zhongli Wang 4*
  • 1 Capital Medical University, Beijing, China
  • 2 Heilongjiang Feihe Dairy Co., Beijing, China
  • 3 Chinese Center For Disease Control and Prevention, Beijing, China
  • 4 Second Hospital of Jiaxing City, Jiaxing, Zhejiang Province, China

The final, formatted version of the article will be published soon.

    The study aims to explore the nutritional composition, growth performance, digestibility, and serum metabolic differences of milk powders from cow, goat, and sheep using LC-MS/MS-based metabolomics in rat models. Sixty male rats were fed milk powder samples, and their feces and urine were then analyzed for fat and protein content. Among all the samples, the sheep milk powder showed highest protein and fat content level, while cow and goat milk powders separately demonstrated higher lactose and carbohydrate levels. Each milk powder had a unique mineral profile, with sheep milk powder containing the highest calcium content. All groups exhibited consistent growth in body weight and high rates of protein and fat digestibility.Metabolomics analysis revealed distinct metabolic profiles, with goat milk powder linked to steroid hormone biosynthesis and sheep milk powder associated with hormone regulation and bile acid pathways. The study indicates that understanding the sources of milk is crucial for effective dietary planning.

    Keywords: nutritional composition, growth performance, Digestibility, Metabolomics profiles, Cow milk, Goat milk, sheep milk, rat models

    Received: 07 May 2024; Accepted: 01 Nov 2024.

    Copyright: © 2024 Yang, Pan, Pang, Shuang, Liu, Zhang, Song, Ren and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Jiancun Pan, Heilongjiang Feihe Dairy Co., Beijing, China
    Shaojie Pang, Heilongjiang Feihe Dairy Co., Beijing, China
    Hu Shuang, Capital Medical University, Beijing, China
    Miao Liu, Capital Medical University, Beijing, China
    Xinyan Zhang, Heilongjiang Feihe Dairy Co., Beijing, China
    Liping Song, Heilongjiang Feihe Dairy Co., Beijing, China
    Xiangnan Ren, Chinese Center For Disease Control and Prevention, Beijing, 102206, China
    Zhongli Wang, Second Hospital of Jiaxing City, Jiaxing, 314000, Zhejiang Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.