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ORIGINAL RESEARCH article
Front. Nutr.
Sec. Nutrition and Metabolism
Volume 11 - 2024 |
doi: 10.3389/fnut.2024.1428938
Compar ative analysis of the nutr itional composition, digestibility, metabolomics pr ofiles and gr owth influence of cow, goat and sheep milk powder diets in r at models
Provisionally accepted- 1 Capital Medical University, Beijing, China
- 2 Heilongjiang Feihe Dairy Co., Beijing, China
- 3 Chinese Center For Disease Control and Prevention, Beijing, China
- 4 Second Hospital of Jiaxing City, Jiaxing, Zhejiang Province, China
The study aims to explore the nutritional composition, growth performance, digestibility, and serum metabolic differences of milk powders from cow, goat, and sheep using LC-MS/MS-based metabolomics in rat models. Sixty male rats were fed milk powder samples, and their feces and urine were then analyzed for fat and protein content. Among all the samples, the sheep milk powder showed highest protein and fat content level, while cow and goat milk powders separately demonstrated higher lactose and carbohydrate levels. Each milk powder had a unique mineral profile, with sheep milk powder containing the highest calcium content. All groups exhibited consistent growth in body weight and high rates of protein and fat digestibility.Metabolomics analysis revealed distinct metabolic profiles, with goat milk powder linked to steroid hormone biosynthesis and sheep milk powder associated with hormone regulation and bile acid pathways. The study indicates that understanding the sources of milk is crucial for effective dietary planning.
Keywords: nutritional composition, growth performance, Digestibility, Metabolomics profiles, Cow milk, Goat milk, sheep milk, rat models
Received: 07 May 2024; Accepted: 01 Nov 2024.
Copyright: © 2024 Yang, Pan, Pang, Shuang, Liu, Zhang, Song, Ren and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Jiancun Pan, Heilongjiang Feihe Dairy Co., Beijing, China
Shaojie Pang, Heilongjiang Feihe Dairy Co., Beijing, China
Hu Shuang, Capital Medical University, Beijing, China
Miao Liu, Capital Medical University, Beijing, China
Xinyan Zhang, Heilongjiang Feihe Dairy Co., Beijing, China
Liping Song, Heilongjiang Feihe Dairy Co., Beijing, China
Xiangnan Ren, Chinese Center For Disease Control and Prevention, Beijing, 102206, China
Zhongli Wang, Second Hospital of Jiaxing City, Jiaxing, 314000, Zhejiang Province, China
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