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ORIGINAL RESEARCH article
Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 |
doi: 10.3389/fnut.2024.1428856
This article is part of the Research Topic Systemic Markers of Muscle Loss – Volume II View all articles
The L-shaped relationship between composite dietary antioxidant index and sarcopenic obesity in elderly adults: A cross-sectional study.
Provisionally accepted- Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China
Background: This study aimed to examine the independent and combined associations of Composite Dietary Antioxidant Index (CDAI) with sarcopenic obesity (SO) using the National Health and Nutrition Examination Survey (NHANES) database.Methods: Data was gathered from NHANES between 2001 and 2004. To examine the relationship between CDAI and the occurrence of SO, multiple logistic regression analyses were performed.Subgroup analyses were performed to demonstrate stability of results. Restricted cubic splines were utilized to examine the non-linear correlations.Results: A total of 2,333 individuals were included in the study. In the multivariate logistic regression crude model, we revealed an odds ratio of 0.928 [95% confidence interval (CI), 0.891-0.965, P < 0.001] for the correlation between CDAI and SO. The ORs were 0.626 (95% CI, 0.463-0.842) and 0.487 (95% CI, 0.354-0.667) for CDAI tertiles 2 and 3, respectively (p for trend < 0.001), after full adjusted. The subgroup analysis findings demonstrated a reliable and enduring connection between CDAI and SO across various subgroups. However, the strength of the correlation between CDAI and SO was significantly affected by diabetes (p for interaction = 0.027). Moreover, restricted cubic spline analysis revealed a L-shaped relationship.Conclusions: The present study identified an L-shaped correlation between CDAI and SO in the elderly demographic. The implications of these findings were significant for future studies and the formulation of dietary guidelines.
Keywords: Composite Dietary Antioxidant Index, sarcopenic obesity, NHANES, Diet, Elderly
Received: 07 May 2024; Accepted: 12 Aug 2024.
Copyright: © 2024 Wu, Chen, Shi, Liu, Meng, Zheng and Zhou. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
He Wu, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China
Zhengqing Shi, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China
Jieyu Liu, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China
Ziqi Meng, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China
Chenguo Zheng, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China
Chongjun Zhou, Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, China
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