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Front. Nutr.
Sec. Nutrition Methodology
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1427608
This article is part of the Research Topic Nutritional Indicators and Implications for Human Health View all 4 articles

Precision nutrition-based strategy for management of human diseases and healthy aging: Current progress and challenges forward

Provisionally accepted
Vipin K. Singh Vipin K. Singh 1Hu Xiaohu Hu Xiaohu 2Amit K. Singh Amit K. Singh 3MANOJ K. SOLANKI MANOJ K. SOLANKI 4Pooja Vijayaraghavan Pooja Vijayaraghavan 5Rajpal Srivastav Rajpal Srivastav 5Naveen C. Joshi Naveen C. Joshi 6Madhuree Kumari Madhuree Kumari 7SANDEEP KUMAR SINGH SANDEEP KUMAR SINGH 8Zhen Wang Zhen Wang 2AJAY KUMAR AJAY KUMAR 9*
  • 1 Department of Botany, K.S. Saket P.G. College, Ayodhya, India
  • 2 Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology, Agricultural College, Yulin Normal University, Yulin, 537000, China, Yulin, China
  • 3 Botany Department, B.N. College (T.M.B. University, Bhagalpur) Bhagalpur- India, Bhagalpur, India
  • 4 Plant Cytogenetics and Molecular Biology Group, Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia in Katowice, Katowice, Poland, Katowice, Poland
  • 5 Amity Institute of Biotechnology, Amity University, Sector-125, Noida, Uttar Pradesh 201313, India, Noida, India
  • 6 Amity Institute of Microbial Biotechnology, Amity University, Noida-201313, India, Noida, India
  • 7 Department of Biochemistry, Division of Biological Sciences, Indian Institute of Science (IISc), Bangalore, India
  • 8 Division of Microbiology, ICAR-Indian Agriculture Research Institute, New Delhi-110012, India, Delhi, India
  • 9 Amity Institute of Biotechnology, Amity University, Noida, India

The final, formatted version of the article will be published soon.

    Currently, the treatment of various human ailments is based on different therapeutic approaches including traditional and modern medicine systems. Precision nutrition has come into existence as an emerging approach considering the diverse aspects such as age, sex, genetic and epigenetic makeup, apart from the pathophysiological conditions. The continuously and gradually evolving disciplines of genomics about nutrition have elucidated the importance of genetic variations, epigenetic information, and expression of myriads of genes in disease progression apart from the involvement in modulating therapeutic responses. Further, the investigations have presented the considerable role of gut microbiota comprising of commensal and symbionts performing innumerable activities such as release of bioactive molecules, defense against pathogenic microbes, and regulation of immunity. Noteworthy, the characteristics of the microbiome change depending on host attributes, environmental factors, and habitat, in addition to diet, and therefore can be employed as a biomarker to unravel the response to given food. The specific diet and the components thereof can be suggested for supporting the enrichment of the desired microbial community to some extent as an important part of precision nutrition to achieve not only the goal of human health but also of healthy aging.

    Keywords: biomarker, microbiota, Bioactive constituents, machine learning, algorithm, Immunity

    Received: 04 May 2024; Accepted: 29 Jul 2024.

    Copyright: © 2024 Singh, Xiaohu, Singh, SOLANKI, Vijayaraghavan, Srivastav, Joshi, Kumari, SINGH, Wang and KUMAR. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: AJAY KUMAR, Amity Institute of Biotechnology, Amity University, Noida, India

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.