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ORIGINAL RESEARCH article
Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 |
doi: 10.3389/fnut.2024.1426280
The association between dietary vitamin E intake and c onstipation:The National Health and Nutrition Examination Survey (2005-2010)
Provisionally accepted
Junfeng Cai
1
Danqing Li
1*
Ruijun Xie
1*
Xiaoling Yu
2*
Yuning Wu
1*
Feng Sun
1*
Chenxiong Zhang
1,3*- 1 First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China
- 2 Department of traditional chinese medicine,Sanming First Hospital,Sanming,China, Sanming, China
- 3 Department of Proctology,Yubei Hospital of Traditional Chinese Medicine,Chongqing Yubei District,Chongqing,China, Chongqing, China
This investigation aimed to analyze the association between dietary vitamin E intake and constipation prevalence among U.S. adults.Utilizing data from the National Health and Nutrition Examination Survey (NHANES), th is cross-sectional study assessed vitamin E intake through 24-hour dietary recall and defin ed constipation based on the Bristol Stool Form Scale (BSFS). Logistic regression models were employed to evaluate the relationship between vitamin E intake and constipation, w ith results presented as odds ratios (ORs) and 95% confidence intervals (CIs). Stratified a nalyses were conducted based on covariates such as age, and restricted cubic spline (RCS) models were generated to explore the potential linear or non-linear association.Individuals experiencing constipation exhibited lower vitamin E intake compared to those without constipation. Weighted multivariate logistic regression models demonstrated a ne gative correlation between vitamin E intake and constipation risk, even after adjusting for potential confounding variables. Further RCS analysis revealed a statistically significant n on-linear inverse relationship between vitamin E intake and constipation risk (P-value for non-linearity = 0.0473).Our findings suggest an independent inverse association between vitamin E intake and co nstipation prevalence in U.S. adults. Prospective research is needed to validate these obser vations.
Keywords: Vitamin E, Constipation, NHANES(National Health and Nutrition Examin ation Survey), dietary intake, Population-based Study
Received: 01 May 2024; Accepted: 29 Jul 2024.
Copyright: © 2024 Cai, Li, Xie, Yu, Wu, Sun and Zhang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Danqing Li, First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China
Ruijun Xie, First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China
Xiaoling Yu, Department of traditional chinese medicine,Sanming First Hospital,Sanming,China, Sanming, China
Yuning Wu, First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China
Feng Sun, First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China
Chenxiong Zhang, Department of Proctology,Yubei Hospital of Traditional Chinese Medicine,Chongqing Yubei District,Chongqing,China, Chongqing, China
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