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SYSTEMATIC REVIEW article

Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1421386

Evidence summary of lifestyle interventions in adults with metabolic dysfunction-associated steatotic liver disease

Provisionally accepted
Mei-Jing Chen Mei-Jing Chen 1Ying Chen Ying Chen 2Jin-Qing Lin Jin-Qing Lin 3Rong Hu Rong Hu 1Dun Liu Dun Liu 1Jing-yi Chen Jing-yi Chen 1Ka Li Ka Li 4Xiaoying Jiang Xiaoying Jiang 1*
  • 1 Fujian Medical University, Fuzhou, Fujian Province, China
  • 2 Xiamen Medical College, Xiamen, Fujian Province, China
  • 3 Fuzhou second hospital, Fuzhou, China
  • 4 Sichuan University, Chengdu, Sichuan Province, China

The final, formatted version of the article will be published soon.

    Objective: In this study, our objective was to provide practice recommendations by thoroughly examining lifestyle interventions for adults diagnosed with metabolic dysfunction-associated steatotic liver disease (MASLD). This was achieved through a systematic review of the literature, specifically focusing on lifestyle modification interventions in adults with MASLD. Methods: The PIPOST (Population, Intervention, Professional, Outcome, Setting, and Type of evidence) framework was used to identify the questions for summarizing evidence. Utilizing the 6S model for the hierarchy of evidence, a computerized search was conducted to retrieve articles pertaining to lifestyle interventions for adults with MASLD from websites such as the UpToDate Clinical Advisor, BMJ Best Practice, JBI Library, Cochrane Library, International Guidelines Library, and PubMed, among others. The available research included clinical decisions, clinical practice guidelines, evidence summaries, systematic evaluation, expert consensus, and expert opinions. Two researchers independently evaluated the methodology of the studies, and evidence was subsequently extracted and grouped thematically. Our review encompassed publications from January 2018 to March 2023. Results: A total of 26 publications were identified for the final review, consisting of 7 guidelines, 9 systematic evaluations, and 10 expert consensuses/opinions. From these sources, we derived six themes of evidence: intervention modalities, diet management, exercise management, weight loss management, personalized management, and multidisciplinary collaboration. Conclusion: In the management of adults with MASLD, healthcare professionals should embrace a multidisciplinary team approach, adhere to the best available evidence, and develop structured and personalized interventions based on the best evidence for lifestyle modifications.

    Keywords: Evidence-Based Nursing, evidence summary, lifestyle, metabolicassociated fatty liver disease, Non-alcoholic fatty liver disease

    Received: 28 Apr 2024; Accepted: 08 Nov 2024.

    Copyright: © 2024 Chen, Chen, Lin, Hu, Liu, Chen, Li and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Xiaoying Jiang, Fujian Medical University, Fuzhou, 350108, Fujian Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.