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ORIGINAL RESEARCH article

Front. Nutr.
Sec. Clinical Nutrition
Volume 11 - 2024 | doi: 10.3389/fnut.2024.1400398

Association of Healthy Eating Index-2015 (HEI-2015) and Overactive Bladder: a cross-sectional study

Provisionally accepted
Xuanyu Hao Xuanyu Hao 1Gang Liu Gang Liu 2Dongyang Li Dongyang Li 2*
  • 1 Department of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China
  • 2 Department of Urology, ShengJing Hospital of China Medical University, Shenyang, Liaoning Province, China

The final, formatted version of the article will be published soon.

    Objective: The aim of this cross-sectional study was to investigate the association of HEI-2015 and overactive bladder (OAB) in a large population. Methods: Data was retrieved from the National Health and Nutrition Examination Survey (NHANES) 2005-2020 datasets. Univariate and multivariate logistic regression were performed to evaluate the association between HEI-2015 and OAB. The restricted cubic spline (RCS) model was conducted to investigate the dose-response relationship. Results: Totally, this study included 29,206 participants with 6,184 OAB patients among them. The higher continuous HEI-2015 value was independently associated with lower OAB incidence (OR: 0.87; 95%CI: 0.78, 0.98). Similarly, the highest quartile categorical HEI-2015 was significantly associated with a lower OAB odds (OR:0.72; 95%CI:0.52, 0.99) when compared with the lowest quartile. The RCS curve also showed a favourable non-linear dose-response relationship between HEI-2015 and OAB. Conclusions: A higher HEI-2015 had an favorable association with OAB and there was a non-linear dose-response relationship between them. We suggest adherence to the US diet recommendation as a potential behavioral prevention of OAB. Large-scale long term prospective cohort studies across various regions are needed to verify the findings of this paper.

    Keywords: HEI-2015, OAB, Odds Ratio, dose-response, Cross-sectional study

    Received: 13 Mar 2024; Accepted: 09 Sep 2024.

    Copyright: © 2024 Hao, Liu and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Dongyang Li, Department of Urology, ShengJing Hospital of China Medical University, Shenyang, Liaoning Province, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.