This article is a correction to:
Coral-Derived Endophytic Fungal Product, Butyrolactone-I, Alleviates Lps Induced Intestinal Epithelial Cell Inflammatory Response Through TLR4/NF-κB and MAPK Signaling Pathways: An in vitro and in vivo Studies
Shengwei Chen1,2†
Yi Zhang2,3†
Xueting Niu1,2
Sahar Ghulam Mohyuddin1,2
Jiayin Wen1,2
Minglong Bao1,2Tianyue Yu1,2Lianyun Wu1,2Canyin Hu1,2Yanhong Yong1,2
Xiaoxi Liu2
A. M. Abd El-Aty4,5,6
Xianghong Ju1,2*- 1Department of Veterinary Medicine, Guangdong Ocean University, Zhanjiang, China
- 2Shenzhen Institute of Guangdong Ocean University, Shenzhen, China
- 3College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, China
- 4State Key Laboratory of Bio Based Material and Green Papermaking, College of Food Science and Engineering, Qilu University of Technology, Shandong Academy of Science, Jinan, China
- 5Department of Pharmacology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
- 6Department of Medical Pharmacology, Faculty of Medicine, Atatürk University, Erzurum, Turkey
by Chen, S., Zhang, Y., Niu, X., Mohyuddin, S. G., Wen, J., Bao, M., Yu, T., Wu, L., Hu, C., Yong, Y., Liu, X., Abd El-Aty, A. M., and Ju, X. (2021). Front. Nutr. 8:748118. doi: 10.3389/fnut.2021.748118
In the published article, there was an error in the legend for Figure 3 as published. This sentence previously stated:
“The consequences of BTL-1 on the expression of cytokines were determined by E 50 μM) for 24 h and then treated with LPS (50 μm/mL) for another 1 h.”
The corrected legend appears below.
“Impact of BTL-1 on inflammatory cytokines production in LPS-induced IPEC-J2 cell. The outcome of BTL-1 on IPEC-J2 cell viability (A,B). The consequences of BTL-1 on the expression of cytokines were determined by ELISA (C–F) and qPCR (G–J). The consequences of BTL-1 on the expression of cytokines were determined by ELISA. The cells were treated with BTL-1 (10, 20, and 50 μM) for 24 h and then treated with LPS (50 μg/mL) for another 1 h. The data shown are representative of three independent experiments. The results were expressed as the means ± SEM. #P < 0.05, ##P < 0.01, compared to non-treated group, *P < 0.05, **P < 0.01 compared to LPS group.”
In the published article, there was an error in Table 1 as published. Since our qPCR primers are designed by Shanghai Sangong Biotechnology Co., Ltd., there were a large number of primer sequences in the same account, which led to our submission error. At the same time, we also found that the primer of β-actin gene was missing. The corrected Table 1 and its caption appear below.
TABLE 1
Table 1. Primer sequence.
In the published article, there was an error in Figure 10 as published. Due to the poor shooting effect of some tissue sections, we adjusted the angle of the sections, and the remarks were not clear enough, resulting in mistakenly uploading two images of the same tissue section, namely, the HE staining sections of the low dose group and the medium dose group. The corrected Figure 10 and its caption appear below.
FIGURE 10
Figure 10. The effect of BTL-1 on the intestinal injury of IBD mouse model induced by DSS. Histopathological changes after DSS stimulation in the colon (A). The in vitro intestinal barrier function evaluated by FITC-D fluorescence intensity (B). Upregulation of BTL-1 on tight junction proteins as determined by qPCR (C–E) and western blotting (F–I). The results were expressed as the means ± SEM of n = 3. #P < 0.05, ##P < 0.01, compared to control group, *P < 0.05, **P < 0.01 compared to DSS group.
In the published article, there was an error in Materials and Methods, Subsection “Induction of Experimental Colitis.” This sentence previously stated:
“The animals were randomly allocated to one of the following five groups (n = 5): normal control (only given food and water without DSS), DSS model (administered DSS in drinking water), low-concentration BTL-1 (administered 10 mg/kg DSS, p.o), middle-concentration BTL-1 (taken 20 mg/kg DSS, p.o), and high-concentration BTL-1 group (given 50 mg/kg DSS, p.o) group.”
The corrected sentence appears below:
“The animals were randomly allocated to one of the following five groups (n = 5): normal control (only given food and water without DSS), DSS model (administered DSS in drinking water), low-concentration BTL-1 (administered 1 mg/kg BTL-1, p.o), middle-concentration BTL-1 (taken 2 mg/kg BTL-1, p.o), and high-concentration BTL-1 group (given 5 mg/kg BTL-1, p.o) group.”
The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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Keywords: butyrolactone-I, anti-inflammatory, intestinal barrier, IBD, TLR4/NF-κB, MAPK
Citation: Chen S, Zhang Y, Niu X, Mohyuddin SG, Wen J, Bao M, Yu T, Wu L, Hu C, Yong Y, Liu X, Abd El-Aty AM and Ju X (2023) Corrigendum: Coral-derived endophytic fungal product, butyrolactone-I, alleviates LPS induced intestinal epithelial cell inflammatory response through TLR4/NF-κB and MAPK signaling pathways: An in vitro and in vivo studies. Front. Nutr. 10:1191154. doi: 10.3389/fnut.2023.1191154
Received: 21 March 2023; Accepted: 22 March 2023;
Published: 04 April 2023.
Approved by:
Frontiers Editorial Office, Frontiers Media SA, SwitzerlandCopyright © 2023 Chen, Zhang, Niu, Mohyuddin, Wen, Bao, Yu, Wu, Hu, Yong, Liu, Abd El-Aty and Ju. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Xianghong Ju, juxh77@163.com
†These authors have contributed equally to this work