Frontiers in Neuroscience | Neuropharmacology

Original Research

Published on 04 Apr 2025

Purinergic receptor antagonism reduces interictal discharges and rescues cognitive function in a mouse model of temporal lobe epilepsy

in Neuropharmacology

Nelson Espinosa
Soraya Martín-Suárez
Ariel Lara-Vasquez
Trinidad Montero
Teresa Muro-García
German Fernandez
Juan Manuel Encinas-Pérez
Pablo Fuentealba

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1513135

171 views

Clinical Trial

Accepted on 01 Apr 2025

Exploratory Analysis of Bezisterim Treatment Associated With Decreased Biological Age Acceleration, and Improved Clinical Measure and Biomarker Changes in Mild-to-Moderate Probable Alzheimer's Disease

in Neuropharmacology

Chris Reading
Jiayan Yan
Marcia Testa
Donald Simonson
Hira Javaid
Lisa Schmunk
Daniel Martin-Herranz
Robert Brooke
Juozas Gordevicius
Jeffrey Yangang Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1516746

Original Research

Published on 01 Apr 2025

Abnormal response to chronic social defeat stress and fear extinction in a mouse model of Lynx2-based cholinergic dysregulation

in Neuropharmacology

Kristin R. Anderson
Peter J. Rogu
Talulla B. Palumbo
Julie M. Miwa

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1466166

329 views

Review

Published on 19 Mar 2025

Ferroptosis-associated signaling pathways and therapeutic approaches in depression

in Neuropharmacology

Xuyang Feng
Wenyu Zhang
Xiaoxi Liu
Qiuxuan Wang
Xiao Dang
Jingxian Han
Xuezhu Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1559597

301 views

Mini Review

Published on 18 Mar 2025

Effect and mechanism of GLP-1 on cognitive function in diabetes mellitus

in Neuropharmacology

Xiaoke Dou
Lei Zhao
Jing Li
Yaqiu Jiang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1537898

545 views

Systematic Review

Published on 07 Mar 2025

Effects of neostigmine on postoperative neurocognitive dysfunction: a systematic review and meta-analysis

in Neuropharmacology

Xuelei Zhou
Linlin Chen
Li Zhao
Wei Mao
Xianchun Liu
Longyi Zhang
Ying Xie
Linji Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1464272

533 views

Brief Research Report

Published on 27 Feb 2025

Decoding tinnitus progression: neurochemical shifts in the anterior cingulate cortex revealed by magnetic resonance spectroscopy

in Neuropharmacology

Mengfang Gong
Shuting Han
Yongcong Shen
Yonggang Li
Ji-Sheng Liu
Duo-Duo Tao

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1551106

1,360 views

Original Research

Published on 26 Feb 2025

Chronic unpredictable mild stress induces anxiety-like behavior in female C57BL/6N mice, accompanied by alterations in inflammation and the kynurenine pathway of tryptophan metabolism

in Neuropharmacology

Yanqin Luo
Ning Jiang
Yiwen Zhang
Yongzhi Zhao
Fang Chen
Xueyan Li
Meng Qiang
Guirong Zeng
Qinghu He
Xinmin Liu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1556744

859 views

Review

Published on 19 Feb 2025

Clinical efficacy and potential mechanisms of acupuncture for Parkinson’s disease: the role of GABAergic signaling

in Neuropharmacology

Wenhui Lu
Ting Zhang
Minghui Li
Jun Zhang
Ningning Liu
Lanfang Yang
Guomin Huang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1525486

951 views

Editorial

Published on 19 Feb 2025

Editorial: Therapeutic potential of cannabinoids: from health to disease

in Neuropharmacology

Évila Lopes Salles
Babak Baban
Xu Qin
Valdemar Paffaro

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1565790

634 views

Original Research

Published on 18 Feb 2025

Dezocine modulates the reinstatement of conditioned place preference in morphine-dependent rats via the dopamine reward circuitry

in Neuropharmacology

Yan He
Zhi-Sheng Piao
Yi Jia
Hui-Qi Wu
Xiao-Qiang Wang
Wei-Feng Yu
Fei-Xiang Wu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1507747

587 views

Correction

Published on 17 Feb 2025

Corrigendum: D-serine contributes to seizure development via ERK signaling

in Neuropharmacology

Tie Ma
Yin Wu
Beibei Chen
Wenjuan Zhang
Lang Jin
Chenxi Shen
Yazhou Wang
Yonghong Liu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1541189

340 views

Original Research

Published on 12 Feb 2025

The efficacy of an allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in a murine model of stroke

in Neuropharmacology

Katherine Hernandez
Nathan Jones
Sterling B. Ortega

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1525975

723 views

Original Research

Published on 03 Feb 2025

Dynamic functional connectivity patterns predict early antidepressant treatment response in drug-naïve, first-episode adolescent MDD

in Neuropharmacology

Maojia Ran
Hang Zhang
Meijiang Jin
Yuanmei Tao
Hanmei Xu
Shoukang Zou
Zhujun Wang
Fang Deng
Lijuan Huang
Hong Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1487754

615 views

Original Research

Published on 03 Feb 2025

Ketamine effects on resting state functional brain connectivity in major depressive disorder patients: a hypothesis-driven analysis based on a network model of depression

in Neuropharmacology

Kasper Recourt
Joop Van Gerven
Nadieh Drenth
Jeroen van der Grond
Kantaro Nishigori
Nic J. Van Der Wee
Gabriël E. Jacobs

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1531375

1,174 views

Review

Published on 29 Jan 2025

Role of aquaporins in brain water transport and edema

in Neuropharmacology

Yuyuan Li
Yining Wang
Xingda Huang
Hao Zhang
Youfei Guan
Xiaoyan Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1518967

954 views