Frontiers in Neuroscience | Neurodegeneration

Review

Published on 12 Mar 2025

The role of intracellular and extracellular copper compartmentalization in Alzheimer’s disease pathology and its implications for diagnosis and therapy

in Neurodegeneration

Yu-Qi Li
Shuang-Shuang Tan
Di Wu
Qian Zhang
Tao Wang
Gang Zheng

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1553064

642 views

Original Research

Published on 12 Mar 2025

Phosphorylated neurofilament heavy chain (pNfH) concentration in cerebrospinal fluid predicts overall disease aggressiveness (D50) in amyotrophic lateral sclerosis

in Neurodegeneration

Julia Meyer
Nayana Gaur
Janina von der Gablentz
Bernd Friedrich
Annekathrin Roediger
Julian Grosskreutz
Robert Steinbach

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1536818

591 views

Original Research

Published on 12 Mar 2025

Distinct brain activity patterns associated with traditional Chinese medicine syndromes: a task-fMRI study of mild cognitive impairment

in Neurodegeneration

Zhaoying Li
Shanyu Liu
Yuling Shen
Huan Zhao
Zhenwei Chen
Rui Tan
Zhuoling Li
Ling Quan
Dongdong Yang
Min Shi

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1555365

500 views

Original Research

Accepted on 05 Mar 2025

TREM2 supports neuronal protection and microglial reactivity independently of affecting misfolded protein deposition in chronic neurodegenerative prion disease

in Neurodegeneration

Sarah Marie Carpanini
Barry Matthew Bradford
Alessio Alfieri
Pedro Piccardo
Jimena Monzón-Sandoval
Deborah Brown
Aileen Boyle
Neil A. Mabbott
Jean C. Manson
Barry W McColl

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1525017

183 views

Original Research

Published on 05 Mar 2025

The systemic inflammation markers as potential predictors of disease progression and survival time in amyotrophic lateral sclerosis

in Neurodegeneration

Ye Hong
Jian-Quan Shi
Shuai Feng
Shi-Qi Huang
Zhen-Hua Yuan
Shen Liu
Xiao-Hao Zhang
Jun-Shan Zhou
Teng Jiang
Hong-Dong Zhao

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1552949

697 views

Original Research

Published on 05 Mar 2025

Oxidative stress and inflammation combine to exacerbate cochlear damage and sensorineural hearing loss in C57BL/6 mice

in Neurodegeneration

Zhongwu Su
Yuyan Chen
Yu Liu
Jinyuan Cao
Jie Cui
Haitong Chen
Qi Li

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1563428

615 views

Original Research

Published on 28 Feb 2025

Mutation in Wdr45 leads to early motor dysfunction and widespread aberrant axon terminals in a beta-propeller protein associated neurodegeneration (BPAN) patient-inspired mouse model

in Neurodegeneration

Brandon L. Meyerink
Krishna S. Karia
Mitchell J. Rechtzigel
Prithvi R. Patthi
Ariana C. Edwards
Jessica M. Howard
Elizabeth R. Aaseng
Shamiq Aftab
Jill M. Weimer
Louis-Jan Pilaz

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1545004

1,481 views

Review

Published on 28 Feb 2025

Physical activity and neuroplasticity in neurodegenerative disorders: a comprehensive review of exercise interventions, cognitive training, and AI applications

in Neurodegeneration

Lamia Ben Ezzdine
Wissem Dhahbi
Ismail Dergaa
Halil İbrahim Ceylan
Noomen Guelmami
Helmi Ben Saad
Karim Chamari
Valentina Stefanica
Abdelfatteh El Omri

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1502417

2,546 views

Original Research

Published on 27 Feb 2025

Assessment of the impact of reconstitution therapies—cladribine tablets and alemtuzumab—on the atrophy progression among patients with relapse-remitting multiple sclerosis

in Neurodegeneration

Aleksandra Pogoda-Wesołowska
Ignacy Stachura
Arkadiusz Zegadło
Marzena Maciągowska-Terela
Karolina Sobolewska
Aleksander Dębiec
Jacek Staszewski
Adam Stępień

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1531163

742 views

Original Research

Published on 26 Feb 2025

Persistent homology for MCI classification: a comparative analysis between graph and Vietoris-Rips filtrations

in Neurodegeneration

Debanjali Bhattacharya
Rajneet Kaur
Ninad Aithal
Neelam Sinha
Thomas Gregor Issac

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1518984

650 views

Systematic Review

Published on 25 Feb 2025

Bibliometric analysis of cognitive dysfunction after traumatic brain injury

in Neurodegeneration

Jihua Hu
Ruiting Zhu
Xin Zhang
Yuchen Zhang
Jixin Liu
Wenyang Wang
Chiyin Li
Tong Yang
Ming Zhang
Xuan Niu

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1534735

1,060 views

Review

Published on 20 Feb 2025

The role of Apolipoprotein E4 on cognitive impairment in Parkinson’s disease and Parkinsonisms

in Neurodegeneration

Angenelle Eve Rosal
Sarah L. Martin
Antonio P. Strafella

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1515374

1,584 views

Review

Published on 14 Feb 2025

Application of artificial intelligence in Alzheimer’s disease: a bibliometric analysis

in Neurodegeneration

Sijia Song
Tong Li
Wei Lin
Ran Liu
Yujie Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1511350

1,660 views

Editorial

Published on 14 Feb 2025

Editorial: Neuroinflammation and neurodegenerative diseases

in Neurodegeneration

Pradeep Kumar
Kiran Bhaskar

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1561636

806 views

Review

Published on 12 Feb 2025

TDP-43 as a potential retinal biomarker for neurodegenerative diseases

in Neurodegeneration

Margit Glashutter
Printha Wijesinghe
Joanne A. Matsubara

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1533045

1,808 views
1 citation

Original Research

Published on 07 Feb 2025

Relationship between regional relative theta power and amyloid deposition in mild cognitive impairment: an exploratory study

in Neurodegeneration

Jaesub Park
Woo Jung Kim
Han Wool Jung
Jae-Jin Kim
Jin Young Park

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1510878

756 views