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ORIGINAL RESEARCH article

Front. Neurosci.
Sec. Sleep and Circadian Rhythms
Volume 19 - 2025 | doi: 10.3389/fnins.2025.1534758

Abnormal Power and Spindle Wave Activity During Sleep in Young Smokers

Provisionally accepted
Youwei Dong Youwei Dong *Yongxin Cheng Yongxin Cheng *Juan Wang Juan Wang Zhiwei Ren Zhiwei Ren *Yiming Lu Yiming Lu *Dahua Yu Dahua Yu *Fang Dong Fang Dong *Kai Yuan Kai Yuan *
  • Inner Mongolia University of Science and Technology, Baotou, China

The final, formatted version of the article will be published soon.

    Smoking is associated with significant alterations in sleep architecture. Previous studies have revealed changes in the subjective sleep of young smokers, but research on objective sleep assessment using polysomnography (PSG) is limited. This study aims to explore electroencephalography (EEG) power and sleep spindle activity during the sleep of young smokers, as well as to assess the relationship between sleep and smoking variables. We collected overnight PSG data from 19 young smokers and 16 non-smokers and assessed nicotine dependence and cumulative effects using the Fagerstrom Nicotine Dependence Test (FTND) and pack-year. Compared to the non-smokers, young smokers showed increased alpha power in the frontal and central regions and decreased delta power in the central region. The frontal region showed enhanced sleep spindle duration and density. Notably, both relative alpha power and sleep spindle duration in frontal showed a positive correlation with Pack-year. sleep EEG power and sleep spindle activity in frontal may serve as biomarkers to assess the sleep quality of young smokers. It may improve the understanding of the relationship of sleep and smoking.

    Keywords: Smoking, Sleep spindle wave, Polysomnography, Electroencephalography, power analysis

    Received: 26 Nov 2024; Accepted: 27 Jan 2025.

    Copyright: © 2025 Dong, Cheng, Wang, Ren, Lu, Yu, Dong and Yuan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Youwei Dong, Inner Mongolia University of Science and Technology, Baotou, China
    Yongxin Cheng, Inner Mongolia University of Science and Technology, Baotou, China
    Zhiwei Ren, Inner Mongolia University of Science and Technology, Baotou, China
    Yiming Lu, Inner Mongolia University of Science and Technology, Baotou, China
    Dahua Yu, Inner Mongolia University of Science and Technology, Baotou, China
    Fang Dong, Inner Mongolia University of Science and Technology, Baotou, China
    Kai Yuan, Inner Mongolia University of Science and Technology, Baotou, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.