Frontiers in Neurology | Multiple Sclerosis and Neuroimmunology

Hypothesis and Theory

Published on 25 Sep 2025

System-level hypothesis of dopamine imbalance in early multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Daniele Caligiore
Aurelia Schirripa
Monica Biggio

Frontiers in Neurology

doi 10.3389/fneur.2025.1653134

2,467 views

Brief Research Report

Published on 22 Sep 2025

Peripheral neuromodulation in spasticity-plus syndrome: effects of pulsed radiofrequency on tonic-painful disorders in multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Luigi Di Lorenzo
Carmine D’Avanzo

Frontiers in Neurology

doi 10.3389/fneur.2025.1634960

2,190 views

Original Research

Published on 17 Sep 2025

Serum interleukin-40 increases in anti-AchR antibody-positive myasthenia gravis and correlates with disease activity

in Multiple Sclerosis and Neuroimmunology

Kun Jia
Yingzhe Shao
Taofeng Tan
Xuan Liu
Qiuxia Zhang
Ning Zhao
Li Yang

Frontiers in Neurology

doi 10.3389/fneur.2025.1680530

2,020 views
1 citation

Original Research

Published on 15 Sep 2025

Rituximab retreatment guided by CD27+ B-cell count vs. clinical relapse in anti-MAG polyneuropathy: a cost-effective approach with lower cumulative doses

in Multiple Sclerosis and Neuroimmunology

Margherita Bellucci
Giovanna Capodivento
Federico Massa
Federica Bozzano
Giacomo Bavestrello
Elena Baroncelli
Corrado Cabona
Antonia Cagnetta
Angelo Schenone
Lucilla Nobbio

Frontiers in Neurology

doi 10.3389/fneur.2025.1659670

1,910 views

Brief Research Report

Published on 15 Sep 2025

Major depressive disorder in multiple sclerosis associated with differences in disease modifying therapy and demographics

in Multiple Sclerosis and Neuroimmunology

Nathanael J. Lee
Gavin Hui
C. William Pike
Kristin Galetta
Lucas B. Kipp
Jeffrey Dunn
Scheherazade Le
S. Sai Folmsbee

Frontiers in Neurology

doi 10.3389/fneur.2025.1663778

2,422 views

Original Research

Published on 02 Sep 2025

Autoimmune encephalitis in Latin America. Clinical features and outcomes in pediatric and adult populations: retrospective cohort of The REAL LABIC Project

in Multiple Sclerosis and Neuroimmunology

Miguel A. Vences
Christoper A. Alarcon Ruiz
Mary Marcela Araujo Chumacero
Diego Canales-Pichen
Victor Saquisela
Jesús Domínguez-Rojas
Donoband Melgarejo
Saúl Reyes-Niño
Cintia Johnston
Maricela García-Arellano

Frontiers in Neurology

doi 10.3389/fneur.2025.1647087

2,938 views

Original Research

Published on 28 Aug 2025

Aberrant lncRNA and mRNA expression in patients with anti-N-methyl-d-aspartate receptor encephalitis

in Multiple Sclerosis and Neuroimmunology

Xiaoyu Ma
Wenbo Guo
Zixuan Teng
Qingqing Yin
Chunjuan Wang
Pin Wang
Shougang Guo

Frontiers in Neurology

doi 10.3389/fneur.2025.1605982

1,686 views

Original Research

Published on 26 Aug 2025

Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies

in Multiple Sclerosis and Neuroimmunology

Yutao Liu
Yang Liu
Han Yuan
Limei Wang

Frontiers in Neurology

doi 10.3389/fneur.2025.1634127

2,795 views

Correction

Published on 14 Aug 2025

Correction: Characteristics and correlations of sleep disorders in patients with relapsing–remitting multiple sclerosis in China: a cross-sectional study

in Multiple Sclerosis and Neuroimmunology

Rongrong Wang
Tengteng Zhang
Han Wang
Yao Ren
Runze Zhao
Gaopan Zhang
Guoxun Zhang
Xiongfei Zhao

Frontiers in Neurology

doi 10.3389/fneur.2025.1669440

1,080 views

Review

Published on 30 Jul 2025

Eukaryotic initiation factors: central factor associating mRNA translational plasticity during neuropathic pain progression

in Multiple Sclerosis and Neuroimmunology

Xinshuo Li
Haibo Zhan
Xindan Zhang
Jiayi Li
Xiangrui Li
Xihua Lu
Changhong Miao
Chunli Zhou
Zhen Zhang

Frontiers in Neurology

doi 10.3389/fneur.2025.1566205

2,407 views

Original Research

Published on 28 Jul 2025

Serum homocysteine levels predict poor recovery and relapse in first-attack myelin oligodendrocyte glycoprotein antibody disease

in Multiple Sclerosis and Neuroimmunology

Yanfei Li
Yanjie Jia

Frontiers in Neurology

doi 10.3389/fneur.2025.1619479

2,527 views
1 citation

Review

Published on 25 Jul 2025

Contemporary insights into neuroimmune interactions across development and aging

in Multiple Sclerosis and Neuroimmunology

Xin Yi Yeo
Yunseon Choi
Yeonhee Hong
Hyuk Nam Kwon
Sangyong Jung

Frontiers in Neurology

doi 10.3389/fneur.2025.1611124

3,728 views
3 citations

Original Research

Published on 18 Jul 2025

Autoantibodies against myelin oligodendrocyte glycoprotein in a subgroup of patients with psychotic symptoms

in Multiple Sclerosis and Neuroimmunology

Nikita A. van de Burgt
Laila Kulsvehagen
Marina Mané-Damas
Luc Lutz
Anne-Catherine Lecourt
Clara Monserrat
Anita M. Vinke
Cem İ. Küçükali
Shenghua Zong
Carolin Hoffmann

Frontiers in Neurology

doi 10.3389/fneur.2025.1593042

2,670 views
1 citation

Original Research

Published on 17 Jul 2025

Characteristics and correlations of sleep disorders in patients with relapsing–remitting multiple sclerosis in China: a cross-sectional study

in Multiple Sclerosis and Neuroimmunology

Rongrong Wang
Tengteng Zhang
Han Wang
Yao Ren
Runze Zhao
Gaopan Zhang
Guoxun Zhang
Xiongfei Zhao

Frontiers in Neurology

doi 10.3389/fneur.2025.1608802

1,823 views
2 citations

Original Research

Published on 15 Jul 2025

Mental health outcomes in pregnant women with relapsing-remitting multiple sclerosis: a longitudinal cohort study

in Multiple Sclerosis and Neuroimmunology

Lena Kristina Pfeffer
Caren Ramien
Anja Harrison
Kostas Patas
Kristina Grentzenberg
Stefanie Reinhardt
Andrea Mönch
Max Kaufmann
Stefan M. Gold
Christoph Heesen

Frontiers in Neurology

doi 10.3389/fneur.2025.1619021

2,043 views

Original Research

Published on 11 Jul 2025

Neuropsychiatric disorders among Ecuadorian patients with multiple sclerosis and neuromyelitis optica spectrum disorder

in Multiple Sclerosis and Neuroimmunology

Edgar Patricio Correa-Díaz
Ruth Jimbo Sotomayor
Jorge Rubén Pilco Romero
Patricio Alexander Merino Aguilera

Frontiers in Neurology

doi 10.3389/fneur.2025.1587804

1,954 views
1 citation

Original Research

Published on 10 Jul 2025

Emerging epidemiological trends of multiple sclerosis among adults aged 20–54 years, 1990–2021, with projections to 2035: a systematic analysis for the global burden of disease study 2021

in Multiple Sclerosis and Neuroimmunology

Ling-yun Wang
Wen-fu Wang
Shu-yin Hui
Li Yang
Yue-xian Liu
Hang-juan Li

Frontiers in Neurology

doi 10.3389/fneur.2025.1616245

8,440 views
5 citations

Original Research

Published on 07 Jul 2025

Fatigue and its correlation with anxiety and depression in patients with multiple sclerosis in China

in Multiple Sclerosis and Neuroimmunology

Han Wang
Rongrong Wang
Runze Zhao
Gaopan Zhang
Guoxun Zhang
Xiongfei Zhao

Frontiers in Neurology

doi 10.3389/fneur.2025.1604540

2,283 views
2 citations

Original Research

Published on 04 Jul 2025

FCRL3 genetic variants drive autoimmune pathogenesis in multiple sclerosis and neuromyelitis optica spectrum disorders

in Multiple Sclerosis and Neuroimmunology

Hui-Fen Huang
Qi-Bing Liu
Yong-Feng Xu
Gui-Xian Zhao
Hai-Peng Liu
Hao Yu
Zhi-Ying Wu

Frontiers in Neurology

doi 10.3389/fneur.2025.1552149

2,504 views

Original Research

Published on 03 Jul 2025

Cladribine tablets as therapy for advanced relapsing-remitting multiple sclerosis: a 4-year follow-up real-world, multi-center, retrospective, cohort study

in Multiple Sclerosis and Neuroimmunology

Aleksandra Pogoda-Wesołowska
Adam Stępień
Marcin Wnuk
Monika Marona
Elżbieta Tokarz-Kupczyk
Karolina Piasecka-Stryczyńska
Konrad Rejdak
Anna Jamroz-Wiśniewska
Monika Adamczyk-Sowa
Katarzyna Kubicka-Bączyk

Frontiers in Neurology

doi 10.3389/fneur.2025.1626317

3,958 views
1 citation

Original Research

Published on 16 Jun 2025

Impact of visual discomfort symptoms on SDMT performance among persons with MS

in Multiple Sclerosis and Neuroimmunology

Michelle H. Chen
Timothy J. Rich
Nancy Chiaravalloti
Yael Goverover
Silvana L. Costa

Frontiers in Neurology

doi 10.3389/fneur.2025.1569451

1,765 views

Systematic Review

Published on 30 May 2025

A narrative review of the economic burden of myelin oligodendrocyte glycoprotein antibody-associated disease and analogous conditions

in Multiple Sclerosis and Neuroimmunology

Leonard Lee
Joshua Byrnes
Cathryn Hope
Hansoo Kim

Frontiers in Neurology

doi 10.3389/fneur.2025.1506465

3,221 views
1 citation

Original Research

Published on 29 May 2025

Progression independent of relapsing biology in multiple sclerosis: a real-word study

in Multiple Sclerosis and Neuroimmunology

Heather Y. F. Yong
Carlos Camara-Lemarroy

Frontiers in Neurology

doi 10.3389/fneur.2025.1595929

3,441 views
1 citation

Original Research

Published on 21 May 2025

CONFIDENCE treatment success: long-term real-world effectiveness and safety of ocrelizumab in Germany

in Multiple Sclerosis and Neuroimmunology

Mathias Buttmann
Martin S. Weber
Sven G. Meuth
Sandra Blümich
Stefanie Hieke-Schulz
Petra Dirks
Julius C. Eggebrecht
Tjalf Ziemssen

Frontiers in Neurology

doi 10.3389/fneur.2025.1564327

4,717 views
2 citations

1,192 articles

articles

System-level hypothesis of dopamine imbalance in early multiple sclerosis

Peripheral neuromodulation in spasticity-plus syndrome: effects of pulsed radiofrequency on tonic-painful disorders in multiple sclerosis

Serum interleukin-40 increases in anti-AchR antibody-positive myasthenia gravis and correlates with disease activity

Rituximab retreatment guided by CD27+ B-cell count vs. clinical relapse in anti-MAG polyneuropathy: a cost-effective approach with lower cumulative doses

Major depressive disorder in multiple sclerosis associated with differences in disease modifying therapy and demographics

Autoimmune encephalitis in Latin America. Clinical features and outcomes in pediatric and adult populations: retrospective cohort of The REAL LABIC Project

Aberrant lncRNA and mRNA expression in patients with anti-N-methyl-d-aspartate receptor encephalitis

Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies

Correction: Characteristics and correlations of sleep disorders in patients with relapsing–remitting multiple sclerosis in China: a cross-sectional study

Eukaryotic initiation factors: central factor associating mRNA translational plasticity during neuropathic pain progression

Serum homocysteine levels predict poor recovery and relapse in first-attack myelin oligodendrocyte glycoprotein antibody disease

Contemporary insights into neuroimmune interactions across development and aging

Autoantibodies against myelin oligodendrocyte glycoprotein in a subgroup of patients with psychotic symptoms

Characteristics and correlations of sleep disorders in patients with relapsing–remitting multiple sclerosis in China: a cross-sectional study

Mental health outcomes in pregnant women with relapsing-remitting multiple sclerosis: a longitudinal cohort study

Neuropsychiatric disorders among Ecuadorian patients with multiple sclerosis and neuromyelitis optica spectrum disorder

Emerging epidemiological trends of multiple sclerosis among adults aged 20–54 years, 1990–2021, with projections to 2035: a systematic analysis for the global burden of disease study 2021

Fatigue and its correlation with anxiety and depression in patients with multiple sclerosis in China

FCRL3 genetic variants drive autoimmune pathogenesis in multiple sclerosis and neuromyelitis optica spectrum disorders

Cladribine tablets as therapy for advanced relapsing-remitting multiple sclerosis: a 4-year follow-up real-world, multi-center, retrospective, cohort study

Impact of visual discomfort symptoms on SDMT performance among persons with MS

A narrative review of the economic burden of myelin oligodendrocyte glycoprotein antibody-associated disease and analogous conditions

Progression independent of relapsing biology in multiple sclerosis: a real-word study

CONFIDENCE treatment success: long-term real-world effectiveness and safety of ocrelizumab in Germany

articles

System-level hypothesis of dopamine imbalance in early multiple sclerosis

Peripheral neuromodulation in spasticity-plus syndrome: effects of pulsed radiofrequency on tonic-painful disorders in multiple sclerosis

Serum interleukin-40 increases in anti-AchR antibody-positive myasthenia gravis and correlates with disease activity

Rituximab retreatment guided by CD27+ B-cell count vs. clinical relapse in anti-MAG polyneuropathy: a cost-effective approach with lower cumulative doses

Major depressive disorder in multiple sclerosis associated with differences in disease modifying therapy and demographics

Autoimmune encephalitis in Latin America. Clinical features and outcomes in pediatric and adult populations: retrospective cohort of The REAL LABIC Project

Aberrant lncRNA and mRNA expression in patients with anti-N-methyl-d-aspartate receptor encephalitis

Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies

Correction: Characteristics and correlations of sleep disorders in patients with relapsing–remitting multiple sclerosis in China: a cross-sectional study

Eukaryotic initiation factors: central factor associating mRNA translational plasticity during neuropathic pain progression

Serum homocysteine levels predict poor recovery and relapse in first-attack myelin oligodendrocyte glycoprotein antibody disease

Contemporary insights into neuroimmune interactions across development and aging

Autoantibodies against myelin oligodendrocyte glycoprotein in a subgroup of patients with psychotic symptoms

Characteristics and correlations of sleep disorders in patients with relapsing–remitting multiple sclerosis in China: a cross-sectional study

Mental health outcomes in pregnant women with relapsing-remitting multiple sclerosis: a longitudinal cohort study

Neuropsychiatric disorders among Ecuadorian patients with multiple sclerosis and neuromyelitis optica spectrum disorder

Emerging epidemiological trends of multiple sclerosis among adults aged 20–54 years, 1990–2021, with projections to 2035: a systematic analysis for the global burden of disease study 2021

Fatigue and its correlation with anxiety and depression in patients with multiple sclerosis in China

FCRL3 genetic variants drive autoimmune pathogenesis in multiple sclerosis and neuromyelitis optica spectrum disorders

Cladribine tablets as therapy for advanced relapsing-remitting multiple sclerosis: a 4-year follow-up real-world, multi-center, retrospective, cohort study

Impact of visual discomfort symptoms on SDMT performance among persons with MS

A narrative review of the economic burden of myelin oligodendrocyte glycoprotein antibody-associated disease and analogous conditions

Progression independent of relapsing biology in multiple sclerosis: a real-word study

CONFIDENCE treatment success: long-term real-world effectiveness and safety of ocrelizumab in Germany

Emerging epidemiological trends of multiple sclerosis among adults aged 20–54 years, 1990–2021, with projections to 2035: a systematic analysis for the global burden of disease study 2021