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Original Research

Published on 17 Jun 2021

Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates

in Molecular Signalling and Pathways

  • François-Xavier Cantrelle
  • Anne Loyens
  • Xavier Trivelli
  • Oliver Reimann
  • Clément Despres
  • Neha S. Gandhi
  • Christian P. R. Hackenberger
  • Isabelle Landrieu
  • Caroline Smet-Nocca
Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates
Frontiers in Molecular Neuroscience
doi 10.3389/fnmol.2021.661368
  • 6,398 views
  • 37 citations