Frontiers in Molecular Biosciences | Protein Biochemistry for Basic and Applied Sciences

Original Research

Accepted on 25 Feb 2025

Identification of a neuron-specific ferroptosis in the neurodegenerative mucopolysaccharidosis III (MPSIIIB) model

in Protein Biochemistry for Basic and Applied Sciences

Mathilde Larribau
Myriam Rouahi
Christophe Santiago
Jerome AUSSEIL
Zoubida Karim

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1476513

Review

Published on 20 Feb 2025

Two sides of the same coin: heat shock proteins as biomarkers and therapeutic targets for some complex diseases

in Protein Biochemistry for Basic and Applied Sciences

Xolani Henry Makhoba

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1491227

337 views

Original Research

Published on 13 Feb 2025

Long-term iron supplementation in four patients with X-linked erythropoietic protoporphyria: associations with serum proteins and erythrocyte protoporphyrin levels—a single-centre retrospective study

in Protein Biochemistry for Basic and Applied Sciences

Anna-Elisabeth Minder
Francesca Granata
Franziska van Breemen
Xiaoye Schneider-Yin
Elisabeth I. Minder
Lanja Saleh
Jasmin Barman-Aksözen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1509803

376 views

Mini Review

Published on 03 Feb 2025

Dual targeting carbonic anhydrase inhibitors as promising therapeutic approach: a structural overview

in Protein Biochemistry for Basic and Applied Sciences

Katia D’Ambrosio
Anna Di Fiore
Emma Langella

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1511281

429 views

Mini Review

Published on 07 Jan 2025

The N17 domain of huntingtin as a multifaceted player in Huntington’s disease

in Protein Biochemistry for Basic and Applied Sciences

Hyunju Cho

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1527313

651 views

Original Research

Published on 07 Jan 2025

Anticarcinogenic cationic peptides derived from tryptic hydrolysis of β-lactoglobulin

in Protein Biochemistry for Basic and Applied Sciences

Eman Ibrahem
Ali Osman
Hefnawy Taha
Mohamed F. Abo El-Maati
Basel Sitohy
Mahmoud Sitohy

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1444457

437 views

Original Research

Published on 01 Nov 2024

Anhydrous microwave synthesis as efficient method for obtaining model advanced glycation end-products

in Protein Biochemistry for Basic and Applied Sciences

Agnieszka Bronowicka-Szydełko
Katarzyna Madziarska
Aleksandra Kuzan
Łukasz Lewandowski
Joanna Adamiec-Mroczek
Jadwiga Pietkiewicz
Maciej Tota
Maciej Ziomek
Wojciech Stach
Tymoteusz Trocha

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1484196

1,435 views

Editorial

Published on 14 Oct 2024

Editorial: Celebrating women’s contribution to protein folding, misfolding, and degradation in honor of Susan Lindquist (1949–2016)

in Protein Biochemistry for Basic and Applied Sciences

Anat Ben-Zvi
Serena Carra
Esti Yeger-Lotem

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1504059

764 views

Original Research

Published on 30 Sep 2024

Visualizing multimerization of plasticity-related gene 5 at the plasma membrane using FLIM-FRET

in Protein Biochemistry for Basic and Applied Sciences

Franziska Köper
Danara Vonk
Malte W. Dirksen
Isabel Gross
Axel Heep
Torsten Plösch
Mark S. Hipp
Anja U. Bräuer

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1478291

1,095 views

Original Research

Published on 21 Aug 2024

Clearing the JUNQ: the molecular machinery for sequestration, localization, and degradation of the JUNQ compartment

in Protein Biochemistry for Basic and Applied Sciences

Sarah Rolli
Chloe A. Langridge
Emily M. Sontag

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1427542

1,355 views
1 citation

Editorial

Published on 19 Aug 2024

Editorial: Enzyme targeting for the development of novel antimicrobials

in Protein Biochemistry for Basic and Applied Sciences

Elena G. Salina
Chunhua Qiao
Laurent R. Chiarelli

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1472318

580 views

Original Research

Published on 30 Jul 2024

Expression of calpastatin hcast 3-25 and activity of the calpain/calpastatin system in human glioblastoma stem cells: possible involvement of hcast 3-25 in cell differentiation

in Protein Biochemistry for Basic and Applied Sciences

Sonia Spinelli
Federica Barbieri
Monica Averna
Tullio Florio
Marco Pedrazzi
Beatrice F. Tremonti
Michela Capraro
Roberta De Tullio

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1359956

1,372 views
1 citation

Editorial

Published on 30 Jul 2024

Editorial: Beyond protein degradation and lysine modification: novel insights into non-canonical ubiquitination

in Protein Biochemistry for Basic and Applied Sciences

Aysegul Sapmaz
Jin Gan
Darragh P. O’Brien
Adán Pinto-Fernández

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1461356

1,152 views

Original Research

Published on 26 Jul 2024

Comprehensive proteomic characterization of urethral stricture disease in the Chinese population

in Protein Biochemistry for Basic and Applied Sciences

Jiangtao Gao
Hui Liu
Lingling Li
Chunmei Guo
Zhiyong Wang
Mengya Cheng
Subei Tan
Lu Chen
Jijing Shi
Hui Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1401970

1,682 views

Correction

Published on 23 Jul 2024

Corrigendum: Assigning function to active site residues of Schistosoma mansoni thioredoxin/glutathione reductase from analysis of transient state reductive half-reactions with variant forms of the enzyme

in Protein Biochemistry for Basic and Applied Sciences

Madison M. Smith
Graham R. Moran

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1455473

549 views

Review

Published on 10 Jul 2024

Inactive metallopeptidase homologs: the secret lives of pseudopeptidases

in Protein Biochemistry for Basic and Applied Sciences

Peter J. Lyons

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1436917

1,126 views

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Articles

Identification of a neuron-specific ferroptosis in the neurodegenerative mucopolysaccharidosis III (MPSIIIB) model

Two sides of the same coin: heat shock proteins as biomarkers and therapeutic targets for some complex diseases

Long-term iron supplementation in four patients with X-linked erythropoietic protoporphyria: associations with serum proteins and erythrocyte protoporphyrin levels—a single-centre retrospective study

Dual targeting carbonic anhydrase inhibitors as promising therapeutic approach: a structural overview

The N17 domain of huntingtin as a multifaceted player in Huntington’s disease

Anticarcinogenic cationic peptides derived from tryptic hydrolysis of β-lactoglobulin

Anhydrous microwave synthesis as efficient method for obtaining model advanced glycation end-products

Editorial: Celebrating women’s contribution to protein folding, misfolding, and degradation in honor of Susan Lindquist (1949–2016)

Visualizing multimerization of plasticity-related gene 5 at the plasma membrane using FLIM-FRET

Clearing the JUNQ: the molecular machinery for sequestration, localization, and degradation of the JUNQ compartment

Editorial: Enzyme targeting for the development of novel antimicrobials

Expression of calpastatin hcast 3-25 and activity of the calpain/calpastatin system in human glioblastoma stem cells: possible involvement of hcast 3-25 in cell differentiation

Editorial: Beyond protein degradation and lysine modification: novel insights into non-canonical ubiquitination

Comprehensive proteomic characterization of urethral stricture disease in the Chinese population

Corrigendum: Assigning function to active site residues of Schistosoma mansoni thioredoxin/glutathione reductase from analysis of transient state reductive half-reactions with variant forms of the enzyme

Inactive metallopeptidase homologs: the secret lives of pseudopeptidases