Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Brief Research Report

Published on 27 Feb 2025

Pilot study: a descriptive-retrospective analysis of SARS-CoV-2 variants distribution and phylogenesis in the Phlegraean area

in Molecular Diagnostics and Therapeutics

Maria Cristina Mazzarella
Stefano Cristiano
Dilia Rea
Nicola Mazzarella
Martina Addeo
Silvia Iannelli
Geppino Falco
Mariarita Brancaccio
Tiziana Angrisano

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1536953

1,055 views

Original Research

Published on 27 Feb 2025

Multitargeted biological actions of polydatin in preventing pseudogout acute attack

in Molecular Diagnostics and Therapeutics

Chiara Baggio
Paola Galozzi
Amelia Damasco
Vanni Lazzarin
Giampietro Ravagnan
Paolo Sfriso
Roberta Ramonda
Leonardo Punzi
Gianmaria Pennelli
Andrea Doria

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1553912

679 views

Original Research

Published on 26 Feb 2025

Identifying potential biomarkers and molecular mechanisms related to arachidonic acid metabolism in vitiligo

in Molecular Diagnostics and Therapeutics

Xiaoqing Li
Li Yang
Longfei Zhu
Jingying Sun
Cuixiang Xu
Lijun Sun

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1536477

870 views

Review

Published on 26 Feb 2025

TRP channels and breast cancer: the role of TRPs in the pathophysiological development

in Molecular Diagnostics and Therapeutics

Yu Zhang
Yanfeng Yi
Yinghao Shu
Xiaochen Ru
Shuaibing He

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1528663

746 views

Original Research

Published on 25 Feb 2025

Q-Der: a next-generation CoQ10 analogue supercharging neuroprotection by combating oxidative stress and enhancing mitochondrial function

in Molecular Diagnostics and Therapeutics

Matteo Micucci
Federico Gianfanti
Sabrina Donati Zeppa
Giosuè Annibalini
Barbara Canonico
Fabiana Fanelli
Roberta Saltarelli
Riham Osman
Mariele Montanari
Daniele Lopez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1525103

660 views

Original Research

Published on 25 Feb 2025

Development of an enzyme-linked immunosorbent assay (ELISA) for determining neutrophil elastase (NE) – a potential useful marker of multi-organ damage observed in COVID-19 and post-Covid-19 (PCS)

in Molecular Diagnostics and Therapeutics

Joanna Adamiec-Mroczek
Joanna Kluz
Sandra Chwałek
Maciej Rabczyński
Kinga Gostomska-Pampuch
Łukasz Lewandowski
Marta Misiuk-Hojło
Beata Ponikowska
Goutam Chourasia
Ilias Dumas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542898

998 views

Correction

Published on 25 Feb 2025

Corrigendum: Role of ARRB1 in prognosis and immunotherapy: a pan-cancer analysis

in Molecular Diagnostics and Therapeutics

Yingquan Ye
Haili Jiang
Yue Wu
Gaoxiang Wang
Yi Huang
Weijie Sun
Mei Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1577764

354 views

Hypothesis and Theory

Published on 25 Feb 2025

Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis

in Molecular Diagnostics and Therapeutics

Xiangyang Wang
Jingxiao Li
Rong Qin
Yi Yin
Jiepin Li
Sitian Lin
Xi Zou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1523494

1,086 views

Original Research

Accepted on 24 Feb 2025

Risk factors of colorectal cancer in middle-aged and elder adults in China: findings from the China Health and Retirement Longitudinal Study (CHARLS)

in Molecular Diagnostics and Therapeutics

Lin Zhang
Yuyan Zhang
Yujia Huo
William Yang Zhao
Aimin Xu
Zhining Liu
Qiaojun Hong
Ailing He
Li Liu
Huiming Tu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1333834

Correction

Accepted on 21 Feb 2025

Corrigendum: Resveratrol improves mitochondrial biogenesisfunction and activates PGC-1α pathway in a preclinical model of early brain injury following subarachnoid hemorrhage

in Molecular Diagnostics and Therapeutics

Jian Zhou
Zaijia Yang
Ruiming Shen
Huiduan Zhen
Wangwang Zhong
Zhenggang Chen
Jianjian Tang
Juan Zhu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1402935

247 views

Original Research

Published on 20 Feb 2025

Immunomagnetic enrichment coupled to PAX8/TP53 molecular pathology approach increases sensitivity in the detection of ovarian cancer cells in ascites

in Molecular Diagnostics and Therapeutics

Ivana Kurelac
Manuela Sollazzo
Monica De Luise
Francesca Nanetti
Laura Lanteri
Luigi D’Angelo
Beatrice Cavina
Simona Corrà
Stefano Miglietta
Sara Milioni

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1537407

702 views

Editorial

Published on 19 Feb 2025

Editorial: Experimental and computational methods in the development of diagnostics and therapeutics for colon cancer

in Molecular Diagnostics and Therapeutics

Muhammad Suleman
Shahid Ali
Farooq Rashid
Faez Iqbal Khan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1568721

650 views

Original Research

Published on 17 Feb 2025

Genome-wide CRISPR/Cas9 screening identifies key profibrotic regulators of TGF-β1-induced epithelial-mesenchymal transformation and pulmonary fibrosis

in Molecular Diagnostics and Therapeutics

Chunjiang Tan
Juan Wang
Xiangrong Ye
Kaidirina Kasimu
Ye Li
Feng Luo
Hui Yi
Yifeng Luo

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1507163

1,331 views

Original Research

Published on 14 Feb 2025

An unfolded protein response (UPR)-signature regulated by the NFKB–miR-29b/c axis fosters tumor aggressiveness and poor survival in bladder cancer

in Molecular Diagnostics and Therapeutics

Jian Zhang
Xiaosong Fan
Yu Chen
Yichao Han
Weixing Yu
Shaolin Zhang
Bicheng Yang
Junlong Zhang
Yanling Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542650

771 views

Original Research

Published on 14 Feb 2025

A CRISPR-Cas-based recombinase polymerase amplification assay for ultra-sensitive detection of active Trypanosoma brucei evansi infections

in Molecular Diagnostics and Therapeutics

Andrés Álvarez-Rodríguez
Zeng Li
Bo-Kyung Jin
Benoit Stijlemans
Peter Geldhof
Stefan Magez

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1512970

1,225 views

Original Research

Published on 13 Feb 2025

Calcium-dependent adhesion protein CDH18, a potential biomarker for prognosis in uterine corpus endometrial carcinoma

in Molecular Diagnostics and Therapeutics

Xiaoxuan Tang
Shanxing Dang
Jie Qiu
Ruilan Zhou
Jing Ling
Limei Zhang
Xiaopeng Peng
Qingyun Li
Jin Liu
Wei Liao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1530253

1,225 views