Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 25 Mar 2025

Role of Ca2+/calmodulin and PI3K/AKT signaling pathways and active ingredients of BaoTaiYin in treatment of recurrent miscarriage

in Molecular Diagnostics and Therapeutics

Li Ji
Anqi Deng
Huiying Chen
Shuangyan Guo
Pingyu Wang
Ruiyi Zhang
Wenyang Chen
Taotao Fan
Lijuan Jiang
Bing Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1573294

1,620 views

Original Research

Published on 24 Mar 2025

Identification and characterization of yeast SNF1 kinase homologs in Leishmania major

in Molecular Diagnostics and Therapeutics

Gaurav Shoeran
Namrata Anand
Upninder Kaur
Kapil Goyal
Rakesh Sehgal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1567703

644 views

Original Research

Published on 21 Mar 2025

Network pharmacology analysis of Lanatoside C: molecular targets and mechanisms in the treatment of ulcerative colitis

in Molecular Diagnostics and Therapeutics

Wenjing Zhu
Zhengjie Zhang
Xinyuan Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1552360

754 views

Original Research

Published on 20 Mar 2025

Empowering limited-resource countries: collaborating with expert centers for diagnosis of primary ciliary dyskinesia

in Molecular Diagnostics and Therapeutics

Mine Yuksel Kalyoncu
Rim Hjeij
Muruvvet Yanaz
Aynur Gulieva
Merve Selcuk Balcı
Şeyda Karabulut
Neval Metin Cakar
Almala Pınar Ergenekon
Ela Erdem Eralp
Yasemin Gokdemir

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1547152

513 views

Review

Published on 19 Mar 2025

Effects of aging on calcium channels in skeletal muscle

in Molecular Diagnostics and Therapeutics

Mingyi Dong
Andrés Daniel Maturana

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558456

923 views

Original Research

Published on 19 Mar 2025

Comparison of two immunotoxins against DLL3 receptor; as an inhibitor for small cell lung cancer

in Molecular Diagnostics and Therapeutics

Mohammad Hossein Ataee
Seyed Ali Mirhosseini
Reza Mirnejad
Hamideh Mahmoodzadeh Hosseini
Jafar Amani

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1506768

641 views

Original Research

Published on 19 Mar 2025

Osteoporotic vertebral fractures and subsequent fractures: risk factors from a retrospective observational study of patients with osteoporosis

in Molecular Diagnostics and Therapeutics

Mingxing Fan
Ran Lu
Jiayuan Wu
Jie Huang
Yanming Fang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558052

544 views

Original Research

Published on 18 Mar 2025

Biomarkers in glioblastoma and degenerative CNS diseases: defining new advances in clinical usefulness and therapeutic molecular target

in Molecular Diagnostics and Therapeutics

Fan Bu
Jifa Zhong
Ruiqian Guan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1506961

487 views

Original Research

Accepted on 13 Mar 2025

TNFAIP8L3 regulation of TGF-β signaling pathway affects the proportion of macrophages during tumor antigen presentation and affects the prognosis of ovarian cancer

in Molecular Diagnostics and Therapeutics

Chaomin Yue
Xiao Zheng
Yuqing Ye
Danyang Li
Yanhong Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1566363

173 views

Original Research

Published on 13 Mar 2025

Investigation of sphingolipid-related genes in lung adenocarcinoma

in Molecular Diagnostics and Therapeutics

Jibin Mao
Li Li
Hui Sun
Jie Han
Jinqiao Li
Chang-Sheng Dong
Hongyu Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548655

633 views

Original Research

Published on 13 Mar 2025

Network pharmacology combined with untargeted metabolomics reveals the intervention mechanism and compatibility of chenpi-rougui herb pair in nonalcoholic fatty liver disease

in Molecular Diagnostics and Therapeutics

Jinlin Xu
Sen Li
Yuehui Jin
Huiwen Yao
Xu Hu
Shan Cao
Huimin Zhou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1553162

869 views

Original Research

Published on 12 Mar 2025

Expression and distribution of activin-follistatin-inhibin axis in the urinary bladder

in Molecular Diagnostics and Therapeutics

Weipu Mao
Tracy Zhang
Huan Chen
Sagar Barge
Zongwei Wang
Aria Olumi
Seth Alper
Weiqun Yu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1519977

715 views

Original Research

Published on 12 Mar 2025

Integrative multi-omics analysis and machine learning refine global histone modification features in prostate cancer

in Molecular Diagnostics and Therapeutics

XiaoFeng He
QinTao Ge
WenYang Zhao
Chao Yu
HuiMing Bai
XiaoTong Wu
Jing Tao
WenHao Xu
Yunhua Qiu
Lei Chen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1557843

1,585 views

Original Research

Published on 07 Mar 2025

Rapamycin combined with osimertinib alleviated non-small cell lung cancer by regulating the PARP, Akt/mTOR, and MAPK/ERK signaling pathways

in Molecular Diagnostics and Therapeutics

Qingrong Ma
Kai Chen
Haiping Xiao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548810

883 views

Original Research

Accepted on 06 Mar 2025

Systematic use of protein free energy changes for classifying variants of uncertain significance: the case of IFT140 in Mainzer-Saldino Syndrome

in Molecular Diagnostics and Therapeutics

Macarena Gajardo
José Luis Guerrero
Bárbara Poblete
Esperanza Bayyad
Ignacio Castro
Jorge Maturana
Jaime Tobar
Victor Faundes
Paola Krall

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561380

Editorial

Published on 27 Feb 2025

Editorial: Role of fibroblast in cancer

in Molecular Diagnostics and Therapeutics

Xuezhen Zeng
Man Liu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1574538

554 views