Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 02 Jun 2023

Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach

in Molecular Diagnostics and Therapeutics

Geovanny Genaro Reivan Ortiz
Carmen Iulia Ciongradi
M. V. N. L. Chaitanya
Jayasankar Narayanan
Mohamed Mohany
Salim S. Al-Rejaie
José Luis Arias-Gonzáles
Ioan Sârbu
Marjan Assefi
Shaik Vaseem Akram

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1189527

4,731 views
3 citations

Review

Published on 01 Jun 2023

PI3K/Akt/Nrf2 mediated cellular signaling and virus-host interactions: latest updates on the potential therapeutic management of SARS-CoV-2 infection

in Molecular Diagnostics and Therapeutics

V. S. Lekshmi
Kumari Asha
Melvin Sanicas
Abhila Asi
U. M. Arya
Binod Kumar

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1158133

5,022 views
14 citations

Original Research

Published on 01 Jun 2023

Hydroxyurea pharmacokinetics and precision dosing in low-resource settings

in Molecular Diagnostics and Therapeutics

Luke R. Smart
Mwesige Charles
Kathryn E. McElhinney
Min Dong
Alexandra Power-Hays
Thad Howard
Alexander A. Vinks
Emmanuela E. Ambrose
Russell E. Ware

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1130206

2,409 views
3 citations

Original Research

Published on 01 Jun 2023

Circulating neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapy

in Molecular Diagnostics and Therapeutics

Chenfei Zhou
Liting Guo
Qu Cai
Wenqi Xi
Fei Yuan
Huan Zhang
Chao Yan
Lei Huang
Zhenggang Zhu
Jun Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1081762

5,287 views
10 citations

Original Research

Published on 31 May 2023

Single-cell RNA-seq uncovers distinct pathways and genes in endothelial cells during atherosclerosis progression

in Molecular Diagnostics and Therapeutics

Min Wu
Yijin Wu
Shulin Tang
Jinsong Huang
Yueheng Wu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1176267

6,517 views
4 citations

Review

Published on 31 May 2023

lncRNAs-EZH2 interaction as promising therapeutic target in cutaneous melanoma

in Molecular Diagnostics and Therapeutics

Michal Wozniak
Malgorzata Czyz

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1170026

3,143 views
5 citations

Original Research

Published on 30 May 2023

Identification of key signaling pathways and hub genes related to immune infiltration in Kawasaki disease with resistance to intravenous immunoglobulin based on weighted gene co-expression network analysis

in Molecular Diagnostics and Therapeutics

Yue Wang
Yinyin Cao
Yang Li
Meifen Yuan
Jin Xu
Jian Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1182512

3,180 views
2 citations

Editorial

Published on 30 May 2023

Editorial: Oxidative stress in degenerative bone and joint diseases: novel molecular mechanisms and therapeutic potential

in Molecular Diagnostics and Therapeutics

Jialiang Lin
Libo Jiang
Ji Tu
Xiangyang Wang
Weishi Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1213380

1,709 views

Original Research

Published on 26 May 2023

Prediction of prognosis and immunotherapy response in breast cancer based on neutrophil extracellular traps-related classification

in Molecular Diagnostics and Therapeutics

Jiajing Zhao
Xiaojun Xie

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165776

4,155 views
12 citations

Review

Published on 26 May 2023

Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches

in Molecular Diagnostics and Therapeutics

Katya Carbone
Fabio Gervasi
Latipa Kozhamzharova
Nazgul Altybaeva
Eda Sönmez Gürer
Javad Sharifi-Rad
Christophe Hano
Daniela Calina

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1157558

4,687 views
9 citations

Methods

Published on 24 May 2023

Unsupervised neural network for single cell Multi-omics INTegration (UMINT): an application to health and disease

in Molecular Diagnostics and Therapeutics

Chayan Maitra
Dibyendu B. Seal
Vivek Das
Rajat K. De

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1184748

4,457 views
5 citations

Review

Published on 23 May 2023

DPP-4 inhibitors for treating T2DM - hype or hope? an analysis based on the current literature

in Molecular Diagnostics and Therapeutics

Kunika Saini
Smriti Sharma
Yousuf Khan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1130625

33,692 views
57 citations

Original Research

Published on 23 May 2023

Identifying a novel cuproptosis-related necroptosis gene subtype-related signature for predicting the prognosis, tumor microenvironment, and immunotherapy of hepatocellular carcinoma

in Molecular Diagnostics and Therapeutics

Yuanxin Shi
Peng Qiu
Kai Zhao
Xiangyu Li
Yunxiang Feng
Zhengdong Deng
Jianming Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1165243

3,618 views

Methods

Published on 22 May 2023

Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids

in Molecular Diagnostics and Therapeutics

Gerarda Cappuccio
Saleh M. Khalil
Sivan Osenberg
Feng Li
Mirjana Maletic-Savatic

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1181965

7,802 views
10 citations

Original Research

Published on 19 May 2023

Venetoclax is a potent hepsin inhibitor that reduces the metastatic and prothrombotic phenotypes of hepsin-expressing colorectal cancer cells

in Molecular Diagnostics and Therapeutics

Maria Carmen Rodenas
Julia Peñas-Martínez
Irene Pardo-Sánchez
David Zaragoza-Huesca
Carmen Ortega-Sabater
Jorge Peña-García
Salvador Espín
Guillermo Ricote
Sofía Montenegro
Francisco Ayala-De La Peña

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1182925

4,808 views
3 citations

Original Research

Published on 19 May 2023

FAM family gene prediction model reveals heterogeneity, stemness and immune microenvironment of UCEC

in Molecular Diagnostics and Therapeutics

Hao Chi
Xinrui Gao
Zhijia Xia
Wanying Yu
Xisheng Yin
Yifan Pan
Gaoge Peng
Xinrui Mao
Alexander Tobias Teichmann
Jing Zhang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1200335

7,531 views
38 citations

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Articles

Identification of novel candidate targets for suppressing ovarian cancer progression through IL-33/ST2 axis components using the system biology approach

PI3K/Akt/Nrf2 mediated cellular signaling and virus-host interactions: latest updates on the potential therapeutic management of SARS-CoV-2 infection

Hydroxyurea pharmacokinetics and precision dosing in low-resource settings

Circulating neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapy

Single-cell RNA-seq uncovers distinct pathways and genes in endothelial cells during atherosclerosis progression

lncRNAs-EZH2 interaction as promising therapeutic target in cutaneous melanoma

Identification of key signaling pathways and hub genes related to immune infiltration in Kawasaki disease with resistance to intravenous immunoglobulin based on weighted gene co-expression network analysis

Editorial: Oxidative stress in degenerative bone and joint diseases: novel molecular mechanisms and therapeutic potential

Prediction of prognosis and immunotherapy response in breast cancer based on neutrophil extracellular traps-related classification

Casticin as potential anticancer agent: recent advancements in multi-mechanistic approaches

Unsupervised neural network for single cell Multi-omics INTegration (UMINT): an application to health and disease

DPP-4 inhibitors for treating T2DM - hype or hope? an analysis based on the current literature

Identifying a novel cuproptosis-related necroptosis gene subtype-related signature for predicting the prognosis, tumor microenvironment, and immunotherapy of hepatocellular carcinoma

Mass spectrometry imaging as an emerging tool for studying metabolism in human brain organoids

Venetoclax is a potent hepsin inhibitor that reduces the metastatic and prothrombotic phenotypes of hepsin-expressing colorectal cancer cells

FAM family gene prediction model reveals heterogeneity, stemness and immune microenvironment of UCEC