Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Accepted on 07 Apr 2025

Mechanism study on the treatment of ulcerative colitis by Gegen Qinlian nano-preparation through promoting M2 macrophage polarization

in Molecular Diagnostics and Therapeutics

Jilei Li
Jiarui Cao
Zhenyu Zhang
Sizhe Wang
Meng Zhu
Lili Yang
Wenhui Ouyang
Chunzheng Ma

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1580874

Original Research

Published on 07 Apr 2025

UPLC-Q-TOF-MS-based unbiased serum metabolomics investigation of cholangiocarcinoma

in Molecular Diagnostics and Therapeutics

Xiaowei Wang
Xuefeng Xu
Ran Jia
Yuanhong Xu
Ping Hu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1549223

236 views

Review

Published on 07 Apr 2025

FOXOs and their roles in acute and chronic neurological disorders

in Molecular Diagnostics and Therapeutics

Yasin Asadi
Rozenn K. Moundounga
Anand Chakroborty
Augustina Pokokiri
Hongmin Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1538472

289 views

Original Research

Published on 04 Apr 2025

Integrated multi-omics analysis reveals the functional and prognostic significance of lactylation-related gene PRDX1 in breast cancer

in Molecular Diagnostics and Therapeutics

Qinqing Wu
Heng Cao
Jiangdong Jin
Dongxu Ma
Yixiao Niu
Yanping Yu
Xiang Wang
Yiqin Xia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1580622

421 views

Original Research

Accepted on 03 Apr 2025

MRI Based Deep Learning Combined Clinical and Imaging Features to Differentiate Medulloblastoma and Ependymoma in Children

in Molecular Diagnostics and Therapeutics

Yasen Yimit
Parhat Yasin
Yue Hao
Abudouresuli Tuersun
Chencui Huang
Jingru Wang
Xiaoguang Zou
Ya Qiu
Yunling Wang
Mayidili Nijiati

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1570860

103 views

Editorial

Published on 03 Apr 2025

Editorial: Crosstalk between metabolism and immunity

in Molecular Diagnostics and Therapeutics

Jie Xiong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1599219

368 views

Brief Research Report

Published on 03 Apr 2025

Determination of sample stability for a broad panel of coagulation parameters and factor assays on the Cobas t 711 analyzer starting from fresh-never-frozen plasma

in Molecular Diagnostics and Therapeutics

Michael Hoffmann
Norbert Gottschalk
Philipp Huber
Vanessa Scheling
Nicole von Allmen
J. Kolja Hegel

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1491239

466 views

Original Research

Published on 02 Apr 2025

LT-YOLO: long-term temporal enhanced YOLO for stenosis detection on invasive coronary angiography

in Molecular Diagnostics and Therapeutics

Jiaxin Li
Xiang Tang
Xuesong Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1558495

338 views

Correction

Published on 01 Apr 2025

Corrigendum: Comprehensive landscape of junctional genes and their association with overall survival of patients with lung adenocarcinoma

in Molecular Diagnostics and Therapeutics

Bin Xie
Ting Wu
Duiguo Hong
Zhe Lu

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1583736

193 views

Review

Published on 31 Mar 2025

The role of CAFs in therapeutic resistance in triple negative breast cancer: an emerging challenge

in Molecular Diagnostics and Therapeutics

Marianna Rita Brogna
Valeria Varone
Michele DelSesto
Gerardo Ferrara

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1568865

504 views

Original Research

Published on 31 Mar 2025

Establishment of a nomogram-based prognostic model (LASSO-Cox regression) for predicting platelet storage lesions under different storage conditions

in Molecular Diagnostics and Therapeutics

Jun Xiao
Huimin Li
Xiaowei Li
Huifen Lei
Zhicai Li
Cuiying Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1561114

363 views

Systematic Review

Published on 26 Mar 2025

Global knowledge mapping of receptor activator of nuclear factor kappa-B ligand in osteoporotic fractures: a bibliometric analysis (2001–2024)

in Molecular Diagnostics and Therapeutics

Shuai Lu
Huaishuang Shen
Minjuan Li
Yiming Luo
Hao Sun
Xian Zhao
Jianming Chen
Ruifeng Bai
Pengli Han
Yejun Zha

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1545109

762 views

Review

Published on 25 Mar 2025

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cells

in Molecular Diagnostics and Therapeutics

Meng Ning
Donghui Lu
Dong Liang
Pei-Gen Ren

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1513993

890 views

Original Research

Published on 25 Mar 2025

Role of Ca2+/calmodulin and PI3K/AKT signaling pathways and active ingredients of BaoTaiYin in treatment of recurrent miscarriage

in Molecular Diagnostics and Therapeutics

Li Ji
Anqi Deng
Huiying Chen
Shuangyan Guo
Pingyu Wang
Ruiyi Zhang
Wenyang Chen
Taotao Fan
Lijuan Jiang
Bing Shen

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1573294

1,580 views

Original Research

Published on 24 Mar 2025

Identification and characterization of yeast SNF1 kinase homologs in Leishmania major

in Molecular Diagnostics and Therapeutics

Gaurav Shoeran
Namrata Anand
Upninder Kaur
Kapil Goyal
Rakesh Sehgal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1567703

635 views

Original Research

Published on 21 Mar 2025

Network pharmacology analysis of Lanatoside C: molecular targets and mechanisms in the treatment of ulcerative colitis

in Molecular Diagnostics and Therapeutics

Wenjing Zhu
Zhengjie Zhang
Xinyuan Wang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1552360

721 views