Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Original Research

Published on 07 Feb 2025

Serum glutathione peroxidase-3 concentration at diagnosis as a biomarker for assessing disease activity and damage of antineutrophil cytoplasmic antibody-associated vasculitis at diagnosis

in Molecular Diagnostics and Therapeutics

Jihye Chung
Jang Woo Ha
Yong-Beom Park
Sang-Won Lee

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1549454

238 views

Original Research

Published on 06 Feb 2025

Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage

in Molecular Diagnostics and Therapeutics

Xiang Chu
Xiyan Zhu
Honghao Xu
Wenbing Zhao
Debin Guo
Xing Chen
Jinze Wu
Lei Li
Hao Wang
Jun Fei

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1492729

233 views

Review

Published on 06 Feb 2025

The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer

in Molecular Diagnostics and Therapeutics

Xiaosi Gu
Xin Hu
Sijia Zhang
Xiaoyu Zhang
Yong Wang
Lianlian Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1540048

187 views

Brief Research Report

Accepted on 05 Feb 2025

Pilot study: a descriptive-retrospective analysis of SARS-CoV-2 variants distribution and phylogenesis in the Phlegraean Area

in Molecular Diagnostics and Therapeutics

Maria Cristina Mazzarella
Stefano Cristiano
Dilia Rea
Nicola Mazzarella
Martina Addeo
Silvia Ianelli
Geppino Falco
Mariarita Brancaccio
Tiziana Angrisano

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1536953

Review

Published on 04 Feb 2025

The role of potential oxidative biomarkers in the prognosis of intracerebral hemorrhage and the exploration antioxidants as possible preventive and treatment options

in Molecular Diagnostics and Therapeutics

Jiayong Yao
Xiaohong Dai
Xueping Yv
Lei Zheng
Jia Zheng
Binglin Kuang
Wei Teng
Weiwei Yu
Mingyue Li
Hongtao Cao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1541230

304 views

Original Research

Published on 03 Feb 2025

Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning

in Molecular Diagnostics and Therapeutics

Jianhui Chen
Qun Li
Xiaofang Liu
Fang Lin
Yaling Jing
Jiayan Yang
Lianfang Zhao

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1529507

310 views

Hypothesis and Theory

Accepted on 31 Jan 2025

Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis

in Molecular Diagnostics and Therapeutics

Xiangyang Wang
Jingxiao Li
Rong Qin
Yi Yin
Jiepin Li
Sitian Lin
Xi Zou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1523494

114 views

Review

Published on 31 Jan 2025

Epigenetic regulation in coronary artery disease: from mechanisms to emerging therapies

in Molecular Diagnostics and Therapeutics

Rui Gao
Meilin Liu
Haoyi Yang
Yuhan Shen
Ni Xia

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1548355

290 views

Original Research

Accepted on 30 Jan 2025

Q-Der: A Next-Generation CoQ10 Analogue Supercharging Neuroprotection by Combating Oxidative Stress and Enhancing Mitochondrial Function

in Molecular Diagnostics and Therapeutics

Michela Battistelli
Matteo Micucci
Federico Gianfanti
Sabrina DONATI ZEPPA
Giosuè Annibalini
BARBARA CANONICO
fabiana fanelli
ROBERTA SALTARELLI
riham osman
mariele montanari

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1525103

Original Research

Accepted on 30 Jan 2025

Identifying potential biomarkers and molecular mechanisms related to arachidonic acid metabolism in vitiligo

in Molecular Diagnostics and Therapeutics

Lijun Sun
Xiaoqing Li
Li Yang
Longfei Zhu
Jingying Sun
Xu Cuixiang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1536477

Original Research

Published on 30 Jan 2025

Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling

in Molecular Diagnostics and Therapeutics

Raquel Arantes Megid
Guilherme Gomes Ribeiro
Izabela Natalia Faria Gomes
Ana Carolina Laus
Letícia Ferro Leal
Luciane Sussuchi da Silva
Abu-Bakr Adetayo Ariwoola
Josiane Mourão Dias
Rui Manuel Reis
Renato Jose da Silva-Oliveira

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1537523

552 views

Original Research

Published on 29 Jan 2025

Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping

in Molecular Diagnostics and Therapeutics

Shaghayegh Soleimani
Ozgur Albayrak
Kayra Somay
Hong Yang
Buket Yigit
Burge Ulukan
Dila Atak
Murat Akyildiz
Metehan Gursoy
Elif Demirtas

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1521811

609 views

Original Research

Published on 28 Jan 2025

Immune cells in thyroid adenoma and carcinoma: uncovering a hidden value of assessing tumor-host interplay and its potential application in thyroid cytopathology

in Molecular Diagnostics and Therapeutics

Iryna Omelianenko
Nazarii Kobyliak
Tetyana Falalyeyeva
Oleksii Seleznov
Pavlina Botsun
Lyudmila Ostapchenko
Oleksandr Korotkyi
Liudmyla Domylivska
Olena Tsyryuk
Galyna Mykhalchyshyn

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1542821

407 views

Mini Review

Published on 28 Jan 2025

Aging, cancer, and autophagy: connections and therapeutic perspectives

in Molecular Diagnostics and Therapeutics

Begoña Zapatería
Esperanza Arias

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1516789

477 views

Original Research

Accepted on 27 Jan 2025

Immunomagnetic enrichment coupled to PAX8/TP53 molecular pathology approach increases sensitivity in the detection of ovarian cancer cells in ascites

in Molecular Diagnostics and Therapeutics

Ivana Kurelac
Manuela Sollazzo
Monica De Luise
Francesca Nanetti
Laura Lanteri
Luigi D'Angelo
Beatrice Cavina
Simona Corrà
Stefano Miglietta
Sara Milioni

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1537407

Review

Accepted on 27 Jan 2025

TRP channels and breast cancer: the role of TRPs in the pathophysiological development

in Molecular Diagnostics and Therapeutics

Yu Zhang
Yanfeng Yi
Yinghao Shu
Xiaochen Ru
Shuaibing He

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1528663

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Articles

Serum glutathione peroxidase-3 concentration at diagnosis as a biomarker for assessing disease activity and damage of antineutrophil cytoplasmic antibody-associated vasculitis at diagnosis

Deciphering the role of miRNA-mRNA interactions in cerebral vasospasm post intracranial hemorrhage

The diagnostic and prognostic significance of HOXC13-AS and its molecular regulatory mechanism in human cancer

Pilot study: a descriptive-retrospective analysis of SARS-CoV-2 variants distribution and phylogenesis in the Phlegraean Area

The role of potential oxidative biomarkers in the prognosis of intracerebral hemorrhage and the exploration antioxidants as possible preventive and treatment options

Potential biomarkers and immune infiltration linking endometriosis with recurrent pregnancy loss based on bioinformatics and machine learning

Jianpi Yangzheng Xiaozheng granule induced ferroptosis to suppress gastric cancer progression through reprogramming lipid metabolism via SCD1/Wnt/β-catenin axis

Epigenetic regulation in coronary artery disease: from mechanisms to emerging therapies

Q-Der: A Next-Generation CoQ10 Analogue Supercharging Neuroprotection by Combating Oxidative Stress and Enhancing Mitochondrial Function

Identifying potential biomarkers and molecular mechanisms related to arachidonic acid metabolism in vitiligo

Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling

Cellular and immune landscape of chronic liver diseases: insights from immunophenotyping

Immune cells in thyroid adenoma and carcinoma: uncovering a hidden value of assessing tumor-host interplay and its potential application in thyroid cytopathology

Aging, cancer, and autophagy: connections and therapeutic perspectives

Immunomagnetic enrichment coupled to PAX8/TP53 molecular pathology approach increases sensitivity in the detection of ovarian cancer cells in ascites

TRP channels and breast cancer: the role of TRPs in the pathophysiological development