Frontiers in Molecular Biosciences | Molecular Diagnostics and Therapeutics

Brief Research Report

Published on 06 Feb 2024

The potential of N2-modified cap analogues for precise genetic manipulation through mRNA engineering

in Molecular Diagnostics and Therapeutics

Karol Kurpiejewski
Anna Stankiewicz-Drogon
Karolina Piecyk
Eliza Rajkowska
Paulina Skrzypczyk
Jingping Geng
Edward Darzynkiewicz
Renata Grzela
Marzena Jankowska-Anyszka

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1269028

1,718 views
1 citation

Original Research

Published on 05 Feb 2024

Virus sequencing performance during the SARS-CoV-2 pandemic: a retrospective analysis of data from multiple rounds of external quality assessment in Austria

in Molecular Diagnostics and Therapeutics

Jeremy V. Camp
Elisabeth Puchhammer-Stöckl
Stephan W. Aberle
Christoph Buchta

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1327699

1,296 views
1 citation

Review

Published on 05 Feb 2024

14-3-3 proteins—a moonlight protein complex with therapeutic potential in neurological disorder: in-depth review with Alzheimer’s disease

in Molecular Diagnostics and Therapeutics

Gholamareza Abdi
Mukul Jain
Nil Patil
Bindiya Upadhyay
Nigam Vyas
Manish Dwivedi
Radhey Shyam Kaushal

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1286536

4,637 views
8 citations

Original Research

Published on 02 Feb 2024

Circulating miR-206, miR-181b, and miR-21 as promising biomarkers in hypothyroidism and their relationship to related hyperlipidemia and hepatic steatosis

in Molecular Diagnostics and Therapeutics

Asmaa Mohammed
Olfat G. Shaker
Mahmoud A. F. Khalil
Abeer K. Abu-El-Azayem
Amira Samy
Shaimaa A. Fathy
Mohamed M. K. AbdElguaad
Fatma A. M. Mahmoud
Randa Erfan

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1307512

2,389 views
1 citation

Original Research

Published on 02 Feb 2024

Comprehensive detection of CRLF2 alterations in acute lymphoblastic leukemia: a rapid and accurate novel approach

in Molecular Diagnostics and Therapeutics

José Vicente Gil
Alberto Miralles
Sandra de las Heras
Esperanza Such
Gayane Avetisyan
Álvaro Díaz-González
Marta Santiago
Carolina Fuentes
José María Fernández
Pilar Lloret

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1362081

3,182 views
3 citations

Original Research

Published on 31 Jan 2024

Longitudinal analysis of external quality assessment of immunoassay-based steroid hormone measurement indicates potential for improvement in standardization

in Molecular Diagnostics and Therapeutics

Laura Vierbaum
Nathalie Weiss
Patricia Kaiser
Marcel Kremser
Folker Wenzel
Mario Thevis
Ingo Schellenberg
Peter B. Luppa

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1345356

2,529 views
1 citation

Editorial

Published on 31 Jan 2024

Editorial: Platelets and their multi-faceted roles in health and disease

in Molecular Diagnostics and Therapeutics

Marta Zarà
Gianni Francesco Guidetti

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1375090

2,262 views
1 citation

Editorial

Published on 25 Jan 2024

Editorial: Molecular mechanisms underlying obesity and their links with other comorbidities

in Molecular Diagnostics and Therapeutics

Julio Plaza-Diaz
Ana I. Álvarez-Mercado
Bilian Yu
Rungroch Sungthong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1334024

3,001 views
1 citation

Review

Published on 24 Jan 2024

The yeast 14-3-3 proteins Bmh1 and Bmh2 regulate key signaling pathways

in Molecular Diagnostics and Therapeutics

Veronika Obsilova
Tomas Obsil

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2024.1327014

3,924 views
1 citation

Original Research

Published on 22 Jan 2024

Integrating clinical and cross-cohort metagenomic features: a stable and non-invasive colorectal cancer and adenoma diagnostic model

in Molecular Diagnostics and Therapeutics

Dan Zhou
Youli Chen
Zehao Wang
Siran Zhu
Lei Zhang
Jun Song
Tao Bai
Xiaohua Hou

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1298679

1,574 views
1 citation

Original Research

Published on 22 Jan 2024

Potential role for vitamin D vs. intermittent fasting in controlling aquaporin-1 and aquaporin-3 expression in HFD-induced urinary bladder alterations in rats

in Molecular Diagnostics and Therapeutics

Hend M. Hassan
Randa El-Gamal
Walaa. H. E. Hamed
Ola Ali Habotta
Mervat Samy
Rasha Elmowafy
Eman Mohamed ElNashar
Mansour Abdullah Alghamdi
Rashid A. Aldahhan
Khulood Mohammed Al-Khater

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1306523

2,294 views
1 citation

Brief Research Report

Published on 22 Jan 2024

Early prognosis prediction in acute myeloid and acute lymphoid leukemia patients using cell-free DNA concentration ratios

in Molecular Diagnostics and Therapeutics

Noreen Grace George
Bhavika Rishi
Amitabh Singh
Sree Vishmaya
Rakesh Kumar
Neetu Kushwaha
Manpreet Kaur
Reena Bhardwaj
Ankur Jain
Aditi Jain

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1333943

2,255 views
2 citations

Mini Review

Published on 19 Jan 2024

Multi-omics approaches to studying gastrointestinal microbiome in the context of precision medicine and machine learning

in Molecular Diagnostics and Therapeutics

Jingyue Wu
Stephanie S. Singleton
Urnisha Bhuiyan
Lori Krammer
Raja Mazumder

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1337373

5,500 views
17 citations

Original Research

Published on 18 Jan 2024

Elucidating the susceptibility to breast cancer: an in-depth proteomic and transcriptomic investigation into novel potential plasma protein biomarkers

in Molecular Diagnostics and Therapeutics

Yang Wang
Kexin Yi
Baoyue Chen
Bailin Zhang
Gao Jidong

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1340917

2,983 views
5 citations

Original Research

Published on 18 Jan 2024

Development and application of an amplified luminescent proximity homogeneous assay-linked immunosorbent assay for the accurate quantification of kidney injury molecule-1

in Molecular Diagnostics and Therapeutics

Yulin Fu
Danqin Sun
Yuan Qin
Tianyu Zheng
Zixuan Zhou
Xiumei Zhou
Xueqin Zhao
Yan Xu
Biao Huang

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1280681

1,459 views

Original Research

Published on 18 Jan 2024

Exploration of the hypoglycemic mechanism of Fuzhuan brick tea based on integrating global metabolomics and network pharmacology analysis

in Molecular Diagnostics and Therapeutics

Xingliang Xiang
Shanqin You
Zhaoxiang Zeng
Jinlin Xu
Yuqi Lin
Yukun Liu
Lijun Zhang
Rongzeng Huang
Chengwu Song
Shuna Jin

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2023.1266156

1,686 views
2 citations

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Articles

The potential of N2-modified cap analogues for precise genetic manipulation through mRNA engineering

Virus sequencing performance during the SARS-CoV-2 pandemic: a retrospective analysis of data from multiple rounds of external quality assessment in Austria

14-3-3 proteins—a moonlight protein complex with therapeutic potential in neurological disorder: in-depth review with Alzheimer’s disease

Circulating miR-206, miR-181b, and miR-21 as promising biomarkers in hypothyroidism and their relationship to related hyperlipidemia and hepatic steatosis

Comprehensive detection of CRLF2 alterations in acute lymphoblastic leukemia: a rapid and accurate novel approach

Longitudinal analysis of external quality assessment of immunoassay-based steroid hormone measurement indicates potential for improvement in standardization

Editorial: Platelets and their multi-faceted roles in health and disease

Editorial: Molecular mechanisms underlying obesity and their links with other comorbidities

The yeast 14-3-3 proteins Bmh1 and Bmh2 regulate key signaling pathways

Integrating clinical and cross-cohort metagenomic features: a stable and non-invasive colorectal cancer and adenoma diagnostic model

Potential role for vitamin D vs. intermittent fasting in controlling aquaporin-1 and aquaporin-3 expression in HFD-induced urinary bladder alterations in rats

Early prognosis prediction in acute myeloid and acute lymphoid leukemia patients using cell-free DNA concentration ratios

Multi-omics approaches to studying gastrointestinal microbiome in the context of precision medicine and machine learning

Elucidating the susceptibility to breast cancer: an in-depth proteomic and transcriptomic investigation into novel potential plasma protein biomarkers

Development and application of an amplified luminescent proximity homogeneous assay-linked immunosorbent assay for the accurate quantification of kidney injury molecule-1

Exploration of the hypoglycemic mechanism of Fuzhuan brick tea based on integrating global metabolomics and network pharmacology analysis